electrocardiographic left ventricular hypertrophy and outcome in hemodialysis patients血液透析患者的心电图描记的左心室肥大和结果.pdfVIP

Electrocardiographic Left Ventricular Hypertrophy and Outcome in Hemodialysis Patients 1 1 1 1 1 1 Seung Jun Kim , Hyung Jung Oh , Dong Eun Yoo , Dong Ho Shin , Mi Jung Lee , Hyoung Rae Kim , Jung 1 1 1 1 1,2 Tak Park , Seung Hyeok Han , Tae-Hyun Yoo , Kyu Hun Choi , Shin-Wook Kang * 1 Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea, 2 Severance Biomedical Science Institute, Brain Korea 21, Yonsei University, Seoul, Korea Abstract Background and Aims: Electrocardiography (ECG) is the most widely used initial screening test for the assessment of left ventricular hypertrophy (LVH), an independent predictor of cardiovascular mortality in patients with end-stage renal disease (ESRD). However, traditional ECG criteria based only on voltage to detect LVH have limited clinical utility for the detection of LVH because of their poor sensitivity. Methods: This prospective observational study was undertaken to compare the prognostic significance of commonly used ECG criteria for LVH, namely Sokolow-Lyon voltage (SV) or voltage-duration product (SP) and Cornell voltage (CV) or voltage-duration product (CP) criteria, and to investigate the association between echocardiographic LV mass index (LVMI) and ECG-LVH criteria in ESRD patients, who consecutively started maintenance hemodialysis (HD) between January 2006 and December 2008. Results: A total of 317 patients, who underwent both ECG and echocardiography, were included. Compared to SV and CV criteria, SP and CP criteria, respectively, correlated more closely with LV