revisiting the marrow metabolic changes after chemotherapy in lymphoma a step towards personalized care回顾在淋巴瘤化疗后骨髓代谢变化一步个性化护理.pdfVIP

Hindawi Publishing Corporation International Journal of Molecular Imaging Volume 2011, Article ID 942063, 6 pages doi:10.1155/2011/942063 Research Article Revisiting the Marrow Metabolic Changes after Chemotherapy in Lymphoma: A Step towards Personalized Care Bingfeng Tang,1 Malaykumar M. Patel,2 Regina H. Wong,2, 3 Daniel Wood,2 Christiana O. Wong,2, 4 Dafang Wu,2 Pek Lan Khong,5 and Ching Yee Oliver Wong2, 6 1 Department of Radiology, The Ohio State University College of Medicine, Columbus, OH 43210, USA 2 Department of Radiology, Oakland University William Beaumont School of Medicine, Royal Oak, MI 48073, USA 3 LSA, The University of Michigan, Ann Arbor, MI 48109, USA 4 Saybrook College, Yale University, New Haven, CT 06511, USA 5 Department of Diagnostic Radiology, University of Hong Kong, Hong Kong, China 6 Positron Diagnostic Center and Medical Cyclotron, Department of Nuclear Medicine, William Beaumont Hospital, 3601 W, Thirteen Mile Road, Royal Oak, MI 48073, USA Correspondence should be addressed to Ching Yee Oliver Wong, owong@ Received 7 June 2011; Accepted 24 June 2011 Academic Editor: Jun Hatazawa Copyright © 2011 Bingfeng Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose. The aims were to correlate individual marrow metabolic changes after chemotherapy with bone marrow biopsy (BMBx) for its potential value of personalized care in lymphoma. Methods. 26 patients (mean age, 58 ± 15 y; 13 female, 13 male) with follicular lymphoma or diffuse large B-cell lymphoma, referred to FDG-PET/CT imaging, who had BMBx from unilateral or bilateral iliac crest(s