role of body mass index, waist-to-height and waist-to-hip ratio in prediction of nonalcoholic fatty liver disease身体质量指数的作用,waist-to-height和腰臀比非酒精性脂肪肝病的预测.pdfVIP

Hindawi Publishing Corporation Gastroenterology Research and Practice Volume 2012, Article ID 362147, 6 pages doi:10.1155/2012/362147 Clinical Study Role of Body Mass Index, Waist-to-Height and Waist-to-Hip Ratio in Prediction of Nonalcoholic Fatty Liver Disease Rui-Dan Zheng, Zhuo-Ran Chen, Jian-Neng Chen, Yan-Hui Lu, and Jie Chen Research and Therapy Center for Liver Disease, The Affi liated Dongnan Hospital of Xiamen University, Fujian, Zhangzhou 363000, China Correspondence should be addressed to Rui-Dan Zheng, zhengruidan@ Received 9 February 2012; Accepted 6 April 2012 Academic Editor: Fabio Farinati Copyright © 2012 Rui-Dan Zheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To investigate the anthropometric indicators that can effectively predict the nonalcoholic fatty liver disease (NAFLD). Methods. The height, body weight, waist and hip circumference were measured, and body mass index (BMI), waist-to-height (WHtR) and waist-to-hip ratio (WHR) were calculated. M-H chi square test, logistic regression analysis, and receiver-operating characteristic (ROC) curve were employed for the analysis of risk factors. Patients or Materials. 490 patients were recruited, of whom 250 were diagnosed as NAFLD and 240 as non-NAFLD (control group). Results. Compared with the control group, the BMI, WHR, and WHtR were significantly higher in patients with NAFLD. Logistic regression analysis showed that BMI and WHR were effective prognostic factors of NAFLD. In addition, WHR plays a more important role in prediction of NAFLD by the area under curve. Conclusion. WHR is closely rel