自制二氧化碳采样器连续监测.DOC

自制二氧化碳采样器连续监测呼气末二氧化碳的临床研究 王钊 朱昭琼 张益 余志豪 遵义医学院附属医院麻醉科 56300 摘要 目的 拟评价非机械通气患者经口/鼻连续无创PETCO2监测的可行性及临床实用性；方法：在10例非机械通气患者中，使用自制成人二氧化碳采样器进行经口/鼻吸O2并连续监测并比较不同氧流量下不同时间点PETCO2图形和读数。同时在40例非机械通气患者中，比较恒定氧流量下不同时段PETCO2与同时点的PvCO2和PaCO2之间的相关性。结果：10个患者在低、中、高O2流量下均可检测到正常形态矩形波形；不同氧流量下不同时间点所测得的PETCO2数值均无统计学意义(P﹥0.05)；恒定氧流量下不同时间点对PETCO2与PaCO2 ，PETCO2与PvCO2进行的Pearson直线相关分析均提示有中度相关性。结论：经鼻/口连续无创监测PETCO2，在不同O2流量下获取呼末数值均具有很好的稳定性，同时具有经济、安全、无创、实用的特点，可以作为危重病人抢救治疗效果的快速监测指标之一。 关键词：自制二氧化碳采样器 监测 呼气末二氧化碳 [中图分类号] R614.1R614.2，R614.3 ［文献标识码］ A Self-Made Carbon Dioxide Sampling Instrument in Continuous Monitoring of End Tidal Carbon Dioxide during operation Wang Zhao, Zhu Zhaoqiong, Zhang yi, Xie Mian, YU Zhihao. Department of Anesthesiology, Zunyi Medical College; Zunyi 563003,China. Abstract Objective: to evaluate the clinical availability and feasibility of consecutive oral/nasal PETCO2 monitoring in patients with non-mechanical ventilation. Method: In 10 patients (n=10) with non-mechanical ventilation, the adult self-made carbon dioxide samplers were used for continual oral/nasal PETCO2 monitoring under different O2 flow at different time points. Meanwhile in 40 patients (n=40) with non-mechanical ventilation, the correlation between PETCO2 and simultaneous PvCO2 and PaCO2 under constant oxygen flow at different time points was compared. Results: the normal square wave can be detected in 10 patients under different oxygen flow (low, intermediate or 作者：王钊，男，学士，副主任医师，麻醉，发表论文6篇，电话Email:wangzhao0412@ *[基金项目]贵州省高层次人才科研条件特助经费项目TZJF-200860) [通信作者]朱昭琼，女，教授，Email:ganzhuzhaoqiong@，电话high rate). The difference between PETCO2 values detected at different oxygen flow and different time point were not significant (P0.05). Pearson correlation analysis indicated that there was intermediate correlation between PETCO2 and simultaneous PaCO2 and PvCO2 under constant oxygen flow at all time point. Conclusion: Great stability could be acquired in the consecutively noninvasive