nicardipine in hypertensive patients in the perioperative（nicardipine高血压患者在围手术期）.docVIP

Nicardipine in hypertensive patients in the perioperative : Hu Xiaqiu Yan Lu Xiaomin Jiang Min Xia [Keywords:] nicardipine, perioperative, and, high blood pressure [Key Words] nicardipine, perioperative, high blood pressure 0 Introduction Perioperative hypertension is organ and tissue oxygenation demonstrated in a variety of factors under the influence of disease, anesthesia, surgical stimulation there is a danger signal. Find good effect, easy to use antihypertensive drug treatment of perioperative hypertension anesthesiologists concerned about the issue. to nearly 5 a hospital nicardipine (Nicardipine) deal with perioperative hypertension, and achieved good results. An object and method 1.1 object emergency and elective surgery patients 128 (male 82, female 46, systolic blood pressuregt; 155 mmHg (1 mmHg = 0.133 kPa), or diastolic blood pressuregt; 95 mmHg in preoperative hypertension, 92 cases, intraoperative 36 cases of high blood pressure. 1.2 Methods 75 cases of anesthesia, 12 cases of nerve block anesthesia, 41 cases of spinal anesthesia, anesthesia, systolic blood pressure higher than 155 mmHg, diastolic blood pressure higher than 95 mmHg and lasted longer than 5 min with hydrochloric nicardipine besylate 0.01 mg / kg, intravenously. micro pump 2 ~ 5 μg / (kg · min) bolus injection, the blood pressure dropped to below 140/85 mmHg every 3 min after the administration record systolic blood pressure, diastolic blood pressure, heart rate, and calculate the systolic blood pressure pulse rate product (RPP), the dynamic observation of STT wave changes and rhythm changes. 2 Results Select a physiological value, before treatment, after treatment, 10, 20, 30, 40 min, the time point of blood pressure, heart rate, RPP, seeking the mean and standard deviation of changes in the indicators before and after treatment using the statistical t-test processing ( Table 1). 3 min after treatment blood pressure was significantly lower (P lt;0.0