about the impact of ultraviolet radiation on the storage of the blood lymphocyte function（紫外线辐射的影响储存的血液淋巴细胞的功能）.docVIP

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about the impact of ultraviolet radiation on the storage of the blood lymphocyte function（紫外线辐射的影响储存的血液淋巴细胞的功能）.doc

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about the impact of ultraviolet radiation on the storage of the blood lymphocyte function（紫外线辐射的影响储存的血液淋巴细胞的功能）

About the impact of ultraviolet radiation on the storage of the blood lymphocyte function Author: Wangbao Yan, Zhang Jiangeng Regina will, Zhu Hongmei, Wang Baoping, Wei Lu [Keywords] lymphocytes [Abstract] AIM: To explore the effects of ultraviolet irradiation on the function of lymphocytes in banked blood. METHODS: Changes of lymphocyte subgroups, lymphocyte activity, lymphocyte transformation, interleukin2 and its receptor were tested before and after ultraviolet irradiation, and after storage for 72 h separately. RESULTS: Ultraviolet irradiation inhibited the lymphocyte activity. As compared with that of the control group, the content of interleukin2 decreased significantly with prolonged storage time (P lt;0.05. Ultraviolet irradiation markedly inhibited the lymphocytes transformation (P lt;0.01. CD3 + , CD4 + and CD8 + lymphocyte subgroups in banked blood decreased as compared with those of prestorage in the two groups, but there was no significant difference between the two groups. CONCLUSION: Ultraviolet irradiation can inhibit lymphocytes activity and lymphocytes transformation and reduce the accumulation of cytokine in banked blood. [Keywords] ultraviolet rays; blood preservation; lymphocytes [Abstract] Objective: To study the impact of ultraviolet radiation of stored blood lymphocyte function. Methods: by the before and after UV irradiation and storage of blood samples determined after 72 h lymphocyte subsets and activity of cytokines. Results: UV irradiated stored blood inhibit the activity of lymphocytes after irradiation with the extension of storage time, the blood IL2 levels were significantly reduced (P lt;0.05, after UV irradiation lymphocyte transformation rate significantly lower than that in the control group (P lt;0.01, control group stand for 72 h with the blood of irradiated group of CD3 +, CD4 +, CD8 + cell subsets were significantly decreased, but no significant difference. conclusion: ultraviolet radiation stored blood inh