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acetyl salicylic acid on the clinical application of new advances(乙酰水杨酸的临床应用新进展)
Acetyl salicylic acid on the clinical application of new advances
[Keywords] acetyl salicylic acid application Acetylsalicylic acid is the most commonly used anti-inflammatory drugs, anti-inflammatory anti-rheumatic effect is strong, and can promote uric acid excretion. In addition, there are anti-platelet aggregation. This product is easily absorbed orally, 1 ~ 2h of blood concentration reached a peak in the body by the lipase-catalyzed hydrolysis of salicylic acid rapidly in the liver metabolism, excretion by the kidney, usually used in a cold, fever, headache, muscle pain, neuralgia and active rheumatoid arthritis.
1 treatment of biliary ascariasis was with acetylsalicylic acid treatment of biliary ascariasis, the effect is significant. Usage: aspirin tablets, 1g / time, 2 or 3 / d, qd 2 ~ 3d. When paroxysmal cramps stop 24h after withdrawal, and then routine deworming.
(2) treatment of menorrhagia caused by whatever reason, menorrhagia, or myometrium with endometrial synthesis and release of PGI2 and PGE excessive, since the PG can cause uterine vasodilation, inhibition of platelet aggregation. Accordingly, aspirin-type drugs used for menorrhagia and many reported that taking indomethacin, mefenamic acid or naproxen, etc. can significantly reduce the blood through.
3 treatment of primary dysmenorrhea primary dysmenorrhea endometrial fluid and peripheral blood levels of PGF2d or PGF2d/PGE2 ratio increased, its symptoms and the body to give PG induction of labor or abortion side effects are quite similar. PG synthase inhibitors reduce the symptoms of pain and light had a marked effect.
4 treatment of eclampsia aura was that pregnant women should not use aspirin and recently a Paris hospital 102 cases of threatened eclampsia risk pregnant women using aspirin 0.15g / d, combined dipyridamole 0.3g / d treatment, Results: The treatment of normal pregnancy is 2 times higher than the control group, no case of pre-eclampsia, and no fetal c
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