acute progress of wegeners granulomatosis clinic experience and review of the literature（急性进展韦格纳肉芽肿病的临床经验和文献之回顾）.docVIP

Acute progress of Wegener’s granulomatosis clinic experience and review of the literature Journal write Network: author: Jia Li, Xia Chu Tak Sun ridge peak Liu Jing Lei Huiping [Abstract] Objective To analyze a case involving the skin, oral mucosa, eye, ear, kidney, lung system rapidly progressive clinical manifestations of WG granulomatosis, clinical early diagnosis, early treatment based on Methods A retrospective analysis of patients with clinical, laboratory examination and treatment, diagnosis of WG granulomatous pulmonary bleeding to death of the patient’s clinical data and results of this case is characterized by: 1. older women .2. involving the skin, oral mucosa, eye, ear, kidney, lung based clinical performance of the WG granuloma, a total duration of more than a month. by the Department of Neurology Treatment of four days invalid transferred to the Department of Nephrology. progression abrupt death after 1 week of treatment due to hemoptysis. conclusion WG granuloma progress abrupt, the diversity of clinical manifestations, misdiagnosed, mistreated. prompted ANCA-associated vascular inflammation, especially the elderly, combined eye, ear, kidney, lung, oral cavity, multi-system disease, should be vigilant, as early as diagnosis, patients with hemoptysis by hormones and cyclophosphamide pulse therapy and hemodialysis effect was not obvious who should be Early plasma exchange to remove the potential pathological ANCA antibodies in the body through the acute risk period may reduce the risk of death. [Keywords:] WG granuloma clinical manifestations of early plasmapheresis A case Female patient, 62 years old. Chief complaint: dizziness January, aggravated with tinnitus, progressive hearing loss, the close relationship between .1 20 days in patients with no obvious incentive to dizziness, showed persistent, balance disorders in standing and walking, shaking, dizziness and postural changes ignore the matter rotation, no diplopia, no palpitatio