advanced metastatic colorectal cancer clinical observation of 51 cases of chemotherapy（先进的转移性结直肠癌51例化疗的临床观察）.docVIP

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advanced metastatic colorectal cancer clinical observation of 51 cases of chemotherapy（先进的转移性结直肠癌51例化疗的临床观察）.doc

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advanced metastatic colorectal cancer clinical observation of 51 cases of chemotherapy（先进的转移性结直肠癌51例化疗的临床观察）

Advanced metastatic colorectal cancer clinical observation of 51 cases of chemotherapy Abstract: Objective: To observe the irinotecan combination therapy for Gio chemotherapy of metastatic colorectal cancer. Methods: 51 cases of suitability for late second-line chemotherapy for advanced metastatic colorectal cancer patients were randomly assigned to the observation group and control group. observation group, 26 cases were treated with irinotecan combined Gio capsules treatment, the control group of 25 patients using FOLF1RI regimen. Results: The median time to progression was significantly higher than the median time to progression (p lt;0.05, the observation group disease control rate was significantly higher (p lt;0.05, two groups differences were significant, the observation group Ⅲ / Ⅳ ‘incidence of adverse events was significantly lower than the control group (pgt; 0.05. Conclusions: Irinotecan combined Gio treatment of metastatic colorectal cancer progression-free survival (PFS) than FOLRIRI program, and two kinds of treatment programs Ⅲ / Ⅳ ‘no significant difference in side effects. irinotecan combined for Gio as metastatic colorectal second-line chemotherapy in advanced colorectal cancer another option. Keywords: Irinotecan for Gio, colorectal cancer, the efficacy Colorectal cancer treated with surgical resection is the preferred, supplemented by radiotherapy, chemotherapy drugs and traditional Chinese medicine, etc. As for how to choose the best solution to be based on different clinical and pathological staging. Their respective advantages, adhere to long-term treatment, Kuanshu patient’s mental state, good psychotherapy, increase nutrition, improve their immune function, in order to obtain better results [1] This paper aims to explore irinotecan combination therapy for Gio effect of chemotherapy in metastatic colorectal cancer . 1 Materials and Methods 1.1 General Information January 2009 - January 2011 51 patients hospitalized suitabil