advances in medicine prevention of cerebral vasospasm（先进的医学预防脑血管痉挛）.docVIP

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advances in medicine prevention of cerebral vasospasm（先进的医学预防脑血管痉挛）.doc

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advances in medicine prevention of cerebral vasospasm（先进的医学预防脑血管痉挛）

Advances in medicine prevention of cerebral vasospasm Keywords: Cerebral vasospasm (Cerebrovascular Spasma, CVS subarachnoid hemorrhage (Subarachnoid Hemorrhage. The SAH serious complications, the most direct consequences caused by the onset of severe headache, disturbance of consciousness, or delayed cerebral ischemia (Delayed Cerebral Ischemia , DCI), and generate the corresponding focal neurological deficit symptoms. above, many clinicians to understand the disease and treatment plan, often repeatedly underwent imaging examination of the brain (such as cranial CT , DSA, etc., so that many patients bear no small spiritual and economic burdens. now widely recognized that CVS after SAH occurred incidence of about 10% to about 60%, there are still quite a lot of SAH patients will not happen What SAH patients prone CVS CVS. actively explore and take early preventive and therapeutic measures still has a very important significance. reviewed the progress in this regard. 1.1 younger the 1 CVS dangerous factors: younger age is an independent risk factor for CVS prone. Study found that age lt;50 years younger crowd prone symptomatic cerebrovascular spasm [1-2]. Reilly that age 4O ~ 59 year-old SAH patients more susceptible to the younger age not only prone CVS, and the event is often more severe [3]. Higher Chen found that severe CVS group was significantly less than the age of the CVS group and mild to moderate CVS group age and degree of age and CVS was the weak negatively correlated [4]. above, mainly because of the younger cerebral arteriosclerosis or mild cerebral vasoconstriction caused by substances such as endothelin, 5 - serotonin is more sensitive due This is the general view of the current. 1.2 The large amount of bleeding (Fisher gradegt; = Ⅲ: large amount of bleeding is not only caused by CVS risk factors and also affect CVS severity of the disease. Currently, the use of Fisher grade (head CT scan findings, Ⅰ : not found in the blood, Ⅱ grad