间歇性充气加压对下肢深静脉血栓形成患者血液流变学地影响.pdfVIP

综述…………………………………………………………………………… 25 攻读学位期间发表的学术论文目录………………………………………… 36 致谢…………………………………………………………………………… 37 间歇性充气加压对下肢深静脉血栓形成患者血 液流变学的影响 中 文 摘 要 目的：观察间歇性充气加压(IPC)对下肢深静脉血栓形成（DVT）患者 的治疗效果，并从血液流变学方面探讨治疗仪的作用机理。方法：2003 年 3 月-2010 年9 月我科收治的243 例下肢深静脉血栓患者，将其中42 例IPC 治疗病例定为A 组实验组，145 例单纯药物治疗病例中选取60 例定为B 组 对照组。观察两组患者血液流变学指标：全血粘度、红细胞聚集指数、红 细胞电泳时间、红细胞变形指数和小腿肿胀消退情况的对比。结果：两组 患者全血粘度、红细胞聚集指数、红细胞电泳时间、红细胞变形指数，在 治疗第 1 天较入院时无差异，组间无差异（P＞0.05），第3 天较入院时有 差异（P＜0.05），组间第 3 天有差异（P＜0.05），两组患者下肢肿胀度均 明显消退，但实验组肿胀消退速度明显快于对照组（P＜0.05）。结论：间 歇性充气加压可有效改变血液流变学状态，改善血液高凝状态，有效缓解 肢体肿胀症状，缩短住院时间。且不增加治疗难度，使用简单，治疗依从 性好。 关键词：下肢深静脉血栓；间歇性充气加压；抗凝溶栓；血液流变学 1 The Intermittent pneumatic compression in the lower extremities of deep veinous thrombosis of the hemorrheologic influence ABSTRACT Objective: To observe intermittent pneumatic compression (IPC) in the lower limbs of deep vein thrombosis (DVT) patients, and from the therapeutic effect of hemarheology aspects discusses therapeutic effect mechanism. Methods: From March 2003 to September 2010, 243 patients with DVT of lower limbs in our hospital, were double-blind randomized into 2 groups. Group B(60) received drug treatment only, besides, group A(42) received drug treatment and Intermittent Pneumatic Compression (IPC). Observe two groups of the hemorrheologic indices and crus swelling of contrast. Results: Both groups whole blood viscosity, plasma viscosity, erythrocyte aggregation index, erythrocyte electrophoresis time, the 1st day of treatment no significant difference when compared with admission, no significant difference between groups (P 0.05),there are differences on