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a new lms algorithm for analysis of atrial fibrillation signals一种新的lms算法进行分析房颤信号
Ciaccio et al. BioMedical Engineering OnLine 2012, 11:15
/content/11/1/15
RESEARCH Open Access
A new LMS algorithm for analysis of atrial
fibrillation signals
1,2* 1 1 1
Edward J Ciaccio , Angelo B Biviano , William Whang and Hasan Garan
* Correspondence: Abstract
ciaccio@
1Department of Medicine – Division
of Cardiology, Columbia University Background: A biomedical signal can be defined by its extrinsic features (x-axis and
Medical Center, New York, USA y-axis shift and scale) and intrinsic features (shape after normalization of extrinsic
2Columbia University, Harkness features). In this study, an LMS algorithm utilizing the method of differential steepest
Pavilion 804, 180 Fort Washington
Avenue, New York, NY 10032, USA descent is developed, and is tested by normalization of extrinsic features in complex
fractionated atrial electrograms (CFAE).
Method: Equations for normalization of x-axis and y-axis shift and scale are first
derived. The algorithm is implemented for real-time analysis of CFAE acquired during
atrial fibrillation (AF). Data was acquired at a 977 Hz sampling rate from 10
paroxysmal and 10 persistent AF patients undergoing clinical electrophysiologic
study and catheter ablation therapy. Over 24 trials, normalization characteristics using
the new algorithm with four weights were compared to the Widrow-Hoff LMS
algorithm with four tapped delays. T
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