a novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression他克莫司血药浓度的一种新颖的方法来预测肝移植患者通过支持向量回归在重症监护室.pdfVIP

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a novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression他克莫司血药浓度的一种新颖的方法来预测肝移植患者通过支持向量回归在重症监护室.pdf

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a novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression他克莫司血药浓度的一种新颖的方法来预测肝移植患者通过支持向量回归在重症监护室

Available online /content/11/4/R83 Vol 11 No 4 Open Access Research A novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression 1 2 2 2 3 Stijn Van Looy *, Thierry Verplancke *, Dominique Benoit , Eric Hoste , Georges Van Maele , Filip De Turck1 and Johan Decruyenaere2 1Ghent University, Department of Information Technology (INTEC), Gaston Crommenlaan 8, Ghent, Belgium 2Ghent University Hospital, Intensive Care Department, De Pintelaan 185, Ghent, Belgium 3Ghent University, Department of Medical Statistics, De Pintelaan 185, Ghent, Belgium * Contributed equally Corresponding author: Thierry Verplancke, Thierry.Verplancke@UGent.be Received: 8 May 2007 Revisions requested: 11 Jul 2007 Revisions received: 23 Jul 2007 Accepted: 26 Jul 2007 Published: 26 Jul 2007 Critical Care 2007, 11:R83 (doi:10.1186/cc6081) This article is online at: /content/11/4/R83 © 2007 Van Looy et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Tacrolimus is an important immunosuppressive data values. Nonlinear RBF SVR, linear SVR, and MLR were drug for organ transplantation patients. It has a narrow performed after selection of clinically relevant input variables therapeutic ra