a polyvinyl alcohol-polyaniline based electro-conductive hydrogel for controlled stimuli-actuable release of indomethacin基于聚乙烯alcohol-polyaniline导电水凝胶为控制stimuli-actuable吲哚美辛的释放.pdfVIP
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a polyvinyl alcohol-polyaniline based electro-conductive hydrogel for controlled stimuli-actuable release of indomethacin基于聚乙烯alcohol-polyaniline导电水凝胶为控制stimuli-actuable吲哚美辛的释放
Polymers 2011, 3, 150-172; doi:10.3390/polym3010150
OPEN ACCESS
polymers
ISSN 2073-4360
/journal/polymers
Article
A Polyvinyl Alcohol-Polyaniline Based Electro-Conductive
Hydrogel for Controlled Stimuli-Actuable Release of
Indomethacin
Tong-Sheng Tsai 1, Viness Pillay 1,*, Yahya E. Choonara 1, Lisa C. du Toit 1, Girish Modi 2,
3 1
Dinesh Naidoo and Pradeep Kumar
1 Department of Pharmacy and Pharmacology, University of the Witwatersrand, 7 York Road,
Parktown, 2193, Johannesburg, South Africa; E-Mails: tong-sheng.tsai@students.wits.ac.za (T.-S.T.);
yahya.choonara@wits.ac.za (Y.E.C.); lisa.dutoit@wits.ac.za (L.C.T.);
pradeep.kumar@students.wits.ac.za (P.K.)
2 Division of Neurosciences, Department of Neurology, University of the Witwatersrand,
Johannesburg, South Africa; E-Mail: gmodicns@mweb.co.za (G.M.)
3 Division of Neurosciences, Department of Neurosurgery, University of the Witwatersrand,
Johannesburg, South Africa; E-Mail: dineshnaidoo@ (D.N.)
* Author to whom correspondence should be addressed; E-Mail: viness.pillay@wits.ac.za;
Tel.: +27-11-717-2274; Fax: +27-86-553-4733.
Received: 8 November 2010; in revised form: 1 December 2010 / Accepted: 29 December 2010 /
Published: 5 January 2011
Abstract: Electro-conductive hydrogels based on poly(vinyl alcohol), crosslinked with
diethyl acetamidomalonate as the hydrogel component, were engineered using polyaniline
as the inherently conductive component, and fabricated in the form of cylindrical devices
to confer electro-actua
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