a promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the japanese populationinterleukin-18基因的启动子单体型与青少年特发性关节炎有关日本人口.pdfVIP

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a promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the japanese populationinterleukin-18基因的启动子单体型与青少年特发性关节炎有关日本人口.pdf

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a promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the japanese populationinterleukin-18基因的启动子单体型与青少年特发性关节炎有关日本人口

Available online /content/8/3/R60 Vol 8 No 3 Open Access Research article A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population 1 2 1 3 4 Tomoko Sugiura , Nobuaki Maeno , Yasushi Kawaguchi , Syuji Takei , Hiroyuki Imanaka , 4 1 1 1 Yoshifumi Kawano , Hisae Terajima-Ichida , Masako Hara and Naoyuki Kamatani 1Institute of Rheumatology, Tokyo Womens Medical University School of Medicine, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, Japan 2Department of Infection and Immunity, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, Japan 3School of Health Sciences, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, Japan 4Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima, Japan Corresponding author: Yasushi Kawaguchi, y-kawa@ior.twmu.ac.jp Received: 4 Jan 2006 Revisions requested: 1 Feb 2006 Revisions received: 7 Feb 2006 Accepted: 22 Feb 2006 Published: 17 Mar 2006 Arthritis Research Therapy 2006, 8:R60 (doi:10.1186/ar1930) This article is online at: /content/8/3/R60 © 2006 Sugiura et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Recently, we reported that genetic polymorphisms within the