a new pyranoxanthone from calophyllum soulattri一个新的pyranoxanthone属soulattri.pdfVIP

a new pyranoxanthone from calophyllum soulattri一个新的pyranoxanthone属soulattri.pdf

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a new pyranoxanthone from calophyllum soulattri一个新的pyranoxanthone属soulattri

Molecules 2011, 16, 3999-4004; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article A New Pyranoxanthone from Calophyllum soulattri Siau Hui Mah, Gwendoline Cheng Lian Ee *, Mawardi Rahmani, Yun Hin Taufiq-Yap, Mohd Aspollah Sukari and Soek Sin Teh Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia * Author to whom correspondence should be addressed; E-Mail: gwen@.my; Tel.: +603-8946-6785. Received: 21 March 2011; in revised form: 8 April 2011 / Accepted: 19 April 2011 / Published: 12 May 2011 Abstract: Our interest on xanthones from the Calophyllum genus has led us to a detailed study on the chemistry of the stem bark of Calophyllum soulattri. This gave one new pyranoxanthone, soulattrin (1), together with three other xanthones, caloxanthone B (2), caloxanthone C (3), macluraxanthone (4), the triterpene friedelin (5) and the steroid stigmasterol (6). The identities of these compounds were established using analyses of 1D and 2D NMR data. Keywords: soulattrin; pyranoxanthone; Calophyllum soulattri; Guttiferae 1. Introduction Calophyllum is widely distributed in Asia, Australia, Africa and Polynesia. Some species of Calophyllum have been used in folk medicine. Previous studies indicated the existence of a variety of secondary metabolites such as xanthones [1], coumarins [2], triterpenoids [3] and flavonoids [4,5] which poss

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