a survey on clinical presentation and nutritional status of infants with suspected cow milk allergy在临床表现和营养状况调查疑似u201c牛奶过敏的婴儿.pdfVIP

Vieira et al. BMC Pediatrics 2010, 10:25 /1471-2431/10/25 R E S E A R C H A R T I C L E Open Access Research article A survey on clinical presentation and nutritional status of infants with suspected cow milk allergy 1 2 3 4 5 6 Mário C Vieira , Mauro B Morais* , José VN Spolidoro , Mauro S Toporovski , Ary L Cardoso , Gabriela TB Araujo , 7 6 Victor Nudelman and Marcelo CM Fonseca Abstract Background: Cows milk is the most common food allergen in infants and the diagnosis of cows milk allergy is difficult, even with the use of several diagnostic tests. Therefore, elimination diets and challenge tests are essential for the diagnosis and treatment of this disorder. The aim of this study is to report the clinical presentation and nutritional status of children evaluated by pediatric gastroenterologists for the assessment of symptoms suggestive of cows milk allergy. Methods: An observational cross-sectional study was performed among 9,478 patients evaluated by 30 pediatric gastroenterologists for 40 days in 5 different geographical regions in Brazil. Clinical data were collected from patients with symptoms suggestive of cows milk allergy. The nutritional status of infants (age ≤ 24 months) seen for the first time was evaluated according to z-scores for weight-for-age, weight-for-height, and height-for-age. Epi-Info (CDC- NCHS, 2000) software was used to calculate z-scores. Results: The prevalence of suspected cows milk allergy in the study population was 5.4% (513/9,478), and the incidence was 2.2% (211/9,478). Among 159 infants seen at first evaluation, 15.1% presented with a low weight-for-age z score ( -2.0 standard deviation - S