four on a single hexose ganglioside sialic acid (gm1) treatment of neonatal hypoxic-ischemic encephalopathy observed（四个在一个己糖神经节苷脂唾液酸(gm1)治疗新生儿缺血脑病）.docVIP

Four on a single hexose ganglioside sialic acid (GM1) treatment of neonatal hypoxic-ischemic encephalopathy observed Paper Network: [Abstract] Objective To evaluate the single four hexose ganglioside sialic acid (GM1 treatment of neonatal hypoxic-ischemic encephalopathy (HIE the curative effect of neonatal hypoxic-ischemic encephalopathy 60 cases divided into GM1 treatment group (n = 30 and the control group (n = 30, groups were neonatal hypoxic-ischemic encephalopathy comprehensive treatment program, and after 3 days after birth to the conventional neurotrophic drugs, the treatment group on this basis, plus with the ganglioside (GM1, 20mg 5% glucose injection 20ml, the once-daily infusion, treatment 7 to 14 days results treatment group 70.0%, 23.33% effective, with a total effective rate 93.33%; control group, markedly 40.0%, 33.33% effective, the total effective rate was 73.33%; total effective difference was statistically significant (P lt;0.05). Conclusion neonatal hypoxic-ischemic encephalopathy on the basis of the conventional treatment of early nerve section glycosides lipid (GM1 treatment can promote hypoxic-ischemic encephalopathy improvement of clinical symptoms, improvement of neonatal hypoxic-ischemic encephalopathy NBNA score, a significant effect, no adverse reactions. [Keywords] neonatal hypoxic-ischemic encephalopathy single ganglioside sialic acid four hexose Hypoxic-ischemic encephalopathy (hypoxic iochemic encephalopathy, HIE is perinatal hypoxia leading to cerebral hypoxic-ischemic damage of a disease is a common neonatal perinatal brain lesions, the clinical disorders of consciousness , changes in muscle tone, convulsions, respiratory failure as the main performance, may be left after-effects, such as epilepsy, cerebral palsy, mental retardation, visual impairment and behavioral abnormalities, is caused by early neonatal death or neonatal period after permanent nervous system in children damage and defects in one of the main intellectu