fludarabine combination chemotherapy in the treatment of previously untreated follicular lymphoma analysis（氟达拉滨联合化疗治疗以前未经治疗的滤泡性淋巴瘤的分析）.docVIP

Fludarabine combination chemotherapy in the treatment of previously untreated follicular lymphoma analysis Abstract: Objective: fludarabine combination chemotherapy in the treatment of previously untreated follicular lymphoma Analysis Methods: The object of study for the hospital diagnosed 40 patients with previously untreated follicular lymphoma patients, of which 17 patients receiving FC regimen, 13 patients R-FC regimen all patients received 3-7 cycles of chemotherapy, the average number of cycles of chemotherapy for four cycles. Results: 40 patients Dada to 26 cases of complete remission, partial remission in 1 case, the total efficiency of 90.0%. conclusion :: fludarabine treatment of previously untreated follicular lymphoma clinical remission rate higher, longer disease-free survival, and adverse reactions can be tolerated. Keywords: fludarabine, follicular lymphoma, previously untreated Inert non-Hodgkin’s lymphoma, the most common type of follicular lymphoma, the tumor until now the most difficult to cure. Visit FL majority of patients already Ⅲ or Ⅳ previous chemotherapy or radiotherapy did not play effectively improve the long-term survival of patients. although FL is generally sensitive to the initial stages of chemotherapy, but the traditional chemotherapy can not be effective mitigation, specific performance to alternate between relapse and remission progress process [1]. Fludarabine is a purine analogues for the inert the NHL has a better therapeutic effect, higher remission ability. Fludarabine single-agent or combination drug chemotherapy is the American Comprehensive Cancer Network strongly recommended therapeutic FL First programs. previously of fludarabine clinical analysis mostly for the treatment of indolent NHL domestic programs for the treatment of FC within a systematic reports This paper mainly discusses fluoride fludarabine combination chemotherapy in the treatment of previously untreated follicular type lymphoma. now report