原创力文档comparisons of 7- to 78-joint ultrasonography scores all different joint combinations show equal response to adalimumab treatment in patients with rheumatoid arthritis7 - 78 -联合超声评分的比较不同联合组合显示平等应对adalimumab治疗类风湿性关节炎患者.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
comparisons of 7- to 78-joint ultrasonography scores all different joint combinations show equal response to adalimumab treatment in patients with rheumatoid arthritis7 - 78 -联合超声评分的比较不同联合组合显示平等应对adalimumab治疗类风湿性关节炎患者
Hammer and Kvien Arthritis Research Therapy 2011, 13:R78
/content/13/3/R78
RESEARCH ARTICLE Open Access
Comparisons of 7- to 78-joint ultrasonography
scores: all different joint combinations show
equal response to adalimumab treatment in
patients with rheumatoid arthritis
*
Hilde Berner Hammer and Tore K Kvien
Abstract
Introduction: The primary objectives were to explore the associations between a comprehensive ultrasonographic
(US) assessment of joints, tendons and bursae and previously described reduced joint counts (7-, 12-, 28- and 44-
joint score) as well as to assess the sensitivity to change of these different US joint combinations during biological
treatment.
Methods: Twenty patients with rheumatoid arthritis (RA) were examined by US (B-mode (BM) and power Doppler
(PD)) with use of a semi-quantitative (0 to 3) score of 78 joints, 36 tendons/tendon groups and two bursae
(hereafter described as the 78-joint score) at baseline and 1, 3, 6 and 12 months after initiating treatment with
adalimumab. BM and PD scores for the different joint combinations were generated.
Results: The reduced joint scores had high correlation coefficients with the 78-joint score at all examinations
(range 0.79 to 0.99 for BM and 0.77 to 0.99 for PD, each P 0.001) and sum BM and PD scores of all the different
joint combinations improved significantly during follow-up ( P ≤ 0.05 to 0.001).
Conclusions: The reduced joint combinations were highly associated to the 78-joint score. Furthermore, all the
joint combinations presently explored responded well to biological treatment. This indicates that an approach
focusing on few joints and tendons gives equivalent information about the inflammatory activity in RA patients as
a comprehensive US examination. The optimal combination of joints and tendons fo
您可能关注的文档
- childhood clumsiness and peer victimization a case--control study of psychiatric patients童年的笨拙和同伴侵害的案件u2014u2014精神病患者的对照研究.pdf
- breakdown of resistance to grapevine downy mildew upon limited deployment of a resistant variety分解的抗葡萄霜霉病抗性品种的限制部署.pdf
- clinical review flow cytometry perspectives in the icu - from diagnosis of infection to monitoring of injury-induced immune dysfunctions在icu临床回顾流式细胞术的角度u2014u2014从感染监测诊断创伤性免疫障碍.pdf
- comparing the performance of the eq-5d and sf-6d when measuring the benefits of alleviating knee pain比较的性能eq-5d sf-6d当测量减轻膝盖疼痛的好处.pdf
- application of cd56, p63 and ck19 immunohistochemistry in the diagnosis of papillary carcinoma of the thyroidcd56、p63和ck19免疫组织化学在甲状腺乳头状癌的诊断.pdf
- comparison of different methods to obtain and store liver biopsies for molecular and histological research比较不同的方法来获取和储存肝脏活检用于分子和组织学研究.pdf
- coexistence of early microinvasive endometrioid adenocarcinoma and cin3 in the uterine cervix in a 32-year-old japanese woman共存的早期microinvasive endometrioid子宫颈腺癌和cin3在32岁的日本女人.pdf
- cardiovascular and renal effects of carperitide and nesiritide in cardiovascular surgery patients a systematic review and meta-analysis心血管和肾脏carperitide和nesiritide心血管手术患者的系统回顾和荟萃分析.pdf
- comparison of classification methods for detecting associations between snps and chick mortality分类比较的方法检测单核苷酸多态性和小鸡死亡率之间的联系.pdf
- comparison of computerized tomography and ultrasound for diagnosing soft tissue abscesses电脑断层摄影术的比较和超声波诊断软组织脓肿.pdf
- comparison of worm control strategies in grazing sheep in denmark比较放牧绵羊在丹麦的蠕虫控制策略.pdf
- comparison on phenolic compounds and antioxidant properties of cabernet sauvignon and merlot wines from four wine grape-growing regions in china比较的酚类化合物和抗氧化特性的赤霞珠和梅鹿辄葡萄酒在中国从四个酒葡萄种植地区.pdf
- comparisons of selection indices achieving predetermined proportional gains选择指数的比较实现预定的比例上涨.pdf
- compartmentation of sucrose during radial transfer in mature sorghum culm分隔的蔗糖在径向转移成熟的高粱茎.pdf
- compatibility of pedigree-based and marker-based relationship matrices for single-step genetic evaluation兼容性pedigree-based和概略介绍关系矩阵的单步遗传评估.pdf
- comparisons of sampling procedures and time of sampling for the detection of salmonella in danish infected chicken flocks raised in floor systems比较取样程序和时间的抽样检测沙门氏菌的丹麦感染鸡群生长在地面系统.pdf
- comparisons of mortality and pre-discharge respiratory outcomes in small-for-gestational-age and appropriate-for-gestational-age premature infants比较死亡率和pre-discharge呼吸道结果small-for-gestational-age和appropriate-for-gestational-age早产儿.pdf
- compartmentalization of lipid peroxidation in sepsis by multidrug-resistant gram-negative bacteria experimental and clinical evidence划分的脂质过氧化作用由耐多药革兰氏阴性细菌败血症实验和临床证据.pdf
- compilation of secondary metabolites from bidens pilosa l.编译的次生代谢物拜登pilosa l。.pdf
- complaints of the arm, neck and shoulder among computer office workers in sudan a prevalence study with validation of an arabic risk factors questionnaire投诉的手臂,脖子和肩膀之间的计算机办公室工作人员在苏丹阿拉伯语的患病率研究验证风险因素调查问卷.pdf
文档评论（0）