complexes of 3dn metal ions with thiosemicarbazones synthesis and antimicrobial activity金属离子配合物3 dn thiosemicarbazones合成和抗菌活性.pdfVIP

Molecules 2007, 12, 782-796 molecules ISSN 1420-3049 Full Paper Complexes of 3dn Metal Ions with Thiosemicarbazones: Synthesis and Antimicrobial Activity Tudor Rosu 1,*, Aurelian Gulea 2, Anca Nicolae 3 and Rodica Georgescu 4 1 Inorganic Chemistry Department, University of Bucharest, 23 Dumbrava Rosie Street, sector 2, Bucharest, Romania 2 Faculty of Chemistry, Inorganic Chemistry Department, USM-R. Moldavia; E-mail: dociu1946@ 3 Organic Chemistry Department, University of Bucharest, 90 – 92 Panduri Bd., sector 4, Bucharest, Romania; E-mail: nicolae.anca@unibuc.ro 4 Nuclear Physics and Engineering Institute “Horia Hulubei”, Bucharest, Romania; E-mail: r_georgescu@irasm.ro * Author to whom correspondence should be addressed; E-mails: t_rosu0101@ or rosu.tudor@unibuc.ro Received: 27 February 2007; in revised form: 5 April 2007 / Accepted: 12 April 2007 / Published: 17 April 2007 Abstract: The chelating behavior of the thiosemicarbazone derivatives of 2-hydroxy-8-R- tricyclo[.2,7]tridecane-13-one (where R = H, CH , C H ) towards Co(II), Ni(II) and 3 6 5 Cu(II) has been investigated by elemental analysis, molar conductivity measurements, UV- VIS, IR, ESR spectroscopy and thermal studies. It was deduced from the experiments performed that the ligands coordinate to metal ions in different ways – neutral bidentate or mononegative bidentate – depending on the nature of R. Also, if metal acetates are used instead of metal chlorides, the ligands coordinate in a mononegative bidentate fashion, reg