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on the common causes of refractory asthma and treatment(难治性哮喘的常见原因和治疗)
On the common causes of refractory asthma and treatment
[Abstract] Objective To discuss the common causes of refractory asthma and treatment Methods for treatment with the diagnosis process. Conclusion GERD (gastro-oesophageal reflux, GER)-induced asthma after acid suppression therapy may be significantly improved asthma symptoms, patients with asthma or repeated inhalation exposure to constantly around the allergens in the environment caused by asthma or other factors, can make patients avoid exposure to these environmental factors, sinusitis can cause asthma symptoms through the treatment of sinusitis to achieve the purpose of improvement.
[Keywords] common causes of refractory asthma treatment 1 GERD (gastro-oesophageal reflux, GER)-induced asthma Osier back in 1892 had pointed out that the medical textbooks, mainly asthma patients know to lunch, dinner in order to avoid an asthma attack caused by eating too much. first proposed in 1976, Mays’ stomach asthma ‘concept. now clear, gastroesophageal reflux (GER) is caused by a common cause of refractory asthma. Shapiro et al reported a group of steroid-dependent asthma, the incidence of GER in patients with high 47 percent. GER patients because of acidic stomach contents of the counter-flow to esophageal stimulation esophagus in the lower section of mucous membrane receptors, through the vagus nerve reflex to cause bronchial smooth muscle spasm, but also because a small amount of stomach contents be mistaken for inhalation, direct stimulation of airway vagal nerve receptors causes airway contraction. These were only given anti-asthma medicines, often poor efficacy, should also be treated GRE.2006 reported in Wong et al, 56.7% of patients with refractory asthma with GER. after acid suppression therapy in these patients significantly improved asthma symptoms The authors concluded stressed the importance of attention to the cause of GER in asthma, the key role of the refractory.
(2) allergen-induced
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