a comparison of y-chromosome variation in sardinia and anatolia is more consistent with cultural rather than demic diffusion of agriculture染色体变异的比较在撒丁岛和安纳托利亚更符合农业文化而不是人体的扩散.pdfVIP
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a comparison of y-chromosome variation in sardinia and anatolia is more consistent with cultural rather than demic diffusion of agriculture染色体变异的比较在撒丁岛和安纳托利亚更符合农业文化而不是人体的扩散
A Comparison of Y-Chromosome Variation in Sardinia
and Anatolia Is More Consistent with Cultural Rather
than Demic Diffusion of Agriculture
1,2. 3. 4,5 4 1
Laura Morelli , Daniela Contu , Federico Santoni , Michael B. Whalen , Paolo Francalacci ,
Francesco Cucca2,6*
` `
1 Dipartimento di Zoologia e Genetica evoluzionistica, Universita di Sassari, Sassari, Italy, 2 Dipartimento di Scienze Biomediche, Universita di Sassari, Sassari, Italy,
3 Laboratorio di Immunogenetica, Ospedale Microcitemico, Cagliari, Italy, 4 Biomedical Application Area, Center for Advanced Studies, Research and Development in
Sardinia (CRS4), Pula, Italy, 5 Swiss Institution for Bioinformatics, University of Geneva, Geneva, Switzerland, 6 Istituto di Neurogenetica e Neurofarmacologia (NN-CNR),
Monserrato, Italy
Abstract
Two alternative models have been proposed to explain the spread of agriculture in Europe during the Neolithic period. The
demic diffusion model postulates the spreading of farmers from the Middle East along a Southeast to Northeast axis.
Conversely, the cultural diffusion model assumes transmission of agricultural techniques without substantial movements of
people. Support for the demic model derives largely from the observation of frequency gradients among some genetic
variants, in particular haplogroups defined by single nucleotide polymorphisms (SNPs) in the Y-chromosome. A recent
network analysis of the R-M269 Y chromosome lineage has purportedly corroborated Neolithic expansion from Anatolia, the
site of diffusion of agriculture. Howev
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