a deletion in the bovine fanci gene compromises fertility by causing fetal death and brachyspina牛fanci基因的缺失导致胎儿死亡和brachyspina生育的妥协.pdfVIP

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2017-09-07 发布于上海
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a deletion in the bovine fanci gene compromises fertility by causing fetal death and brachyspina牛fanci基因的缺失导致胎儿死亡和brachyspina生育的妥协.pdf

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a deletion in the bovine fanci gene compromises fertility by causing fetal death and brachyspina牛fanci基因的缺失导致胎儿死亡和brachyspina生育的妥协

A Deletion in the Bovine FANCI Gene Compromises Fertility by Causing Fetal Death and Brachyspina 1 2 1,3 4 Carole Charlier *, Jorgen Steen Agerholm , Wouter Coppieters , Peter Karlskov-Mortensen , 1 5 1 1,3 4 1 Wanbo Li , Gerben de Jong , Corinne Fasquelle , Latifa Karim , Susanna Cirera , Nadine Cambisano , 1 5 1 4 Naima Ahariz , Erik Mullaart , Michel Georges , Merete Fredholm * ` ` 1 Unit of Animal Genomics, GIGA-R Faculty of Veterinary Medicine, University of Liege (B34), Liege, Belgium, 2 Department of Large Animal Sciences, Faculty of Health ` ` and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark, 3 GIGA-R Genotranscriptomics Core Facility, University of Liege (B34), Liege, Belgium, 4 Division of Genetics and Bioinformatics, Department of Animal and Veterinary Basic Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark, 5 CRV BV, Arnhem, The Netherlands Abstract Fertility is one of the most important traits in dairy cattle, and has been steadily declining over the last decades. We herein use state-of-the-art genomic tools, including high-throughput SNP genotyping and next-generation sequencing, to identify a 3.3 Kb deletion