retrospective study of the incidence of hfmd and seroepidemiology of antibodies against ev71 and coxa16 in prenatal women and their infants回顾性研究手足口病的发病率和seroepidemiology ev71病毒抗体和coxa16产前妇女和她们的婴儿.pdfVIP
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retrospective study of the incidence of hfmd and seroepidemiology of antibodies against ev71 and coxa16 in prenatal women and their infants回顾性研究手足口病的发病率和seroepidemiology ev71病毒抗体和coxa16产前妇女和她们的婴儿
Retrospective Study of the Incidence of HFMD and
Seroepidemiology of Antibodies against EV71 and
CoxA16 in Prenatal Women and Their Infants
1 . 2 . 1. 3 2 1
Feng-Cai Zhu * , Zheng-Lun Liang * , Fan-Yue Meng , Ying Zeng , Qun-Ying Mao , Kai Chu , Xue-
3 2 1 1 1 1 1 1
Fang Song , Xin Yao , Jing-Xin Li , Hong Ji , Yi-Ju Zhang , Liang Li , Hong-Xing Pan , Ke Xu , Wei-
1 4 1 1 2
Ming Dai , Wei-Wei Zhang , Fei Deng , Hua Wang , Jun-Zhi Wang *
1 Acute Infectious Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, People’s Republic of China, 2 Laboratory 2,
National Institutes for Food and Drug Control, Beijing, People’s Republic of China, 3 Shenzhen Kangtai Biological Products Co., Ltd., Shenzhen Science Industry Park,
Guangdong Province, People’s Republic of China, 4 School of Public Health, Southeast University, Nanjing, Jiangsu Province, People’s Republic of China
Abstract
Background: Hand, foot, and mouth disease (HFMD) has been emerging as an important public problem over the past few
decades, especially in Asian and Pacific regions. A national program on EV71 vaccine development against HFMD was
initiated in China, in 2008, which called for a need for seroepidemiological study for the target population.
Methodology/Principal Findings: This was a retrospective study conducted in Jiangsu Province, in October, 2010. We
measured the neutralizing antibodies against EV71 and CoxA16 in a cohort of infants aged of 2, 7, 12, and 27–38 months
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