原创力文档renal function and risk of coronary heart disease in general populations new prospective study and systematic review肾功能和冠心病的风险一般人群新的前瞻性研究和系统综述.pdfVIP
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renal function and risk of coronary heart disease in general populations new prospective study and systematic review肾功能和冠心病的风险一般人群新的前瞻性研究和系统综述
PLoS MEDICINE
Renal Function and Risk of Coronary
Heart Disease in General Populations:
New Prospective Study and Systematic Review
1 1* 2 2,3
Emanuele Di Angelantonio , John Danesh , Gudny Eiriksdottir , Vilmundur Gudnason
1 Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, 2 Icelandic Heart Association, Kopavogur, Iceland, 3 University of
Iceland, Reykjavik, Iceland
Funding: This study was supported A B S T R A C T
by a programme grant from the
British Heart Foundation (JD and VG)
and by the Raymond and Beverly
Sackler Research Award in the Background
Medical Sciences (JD). Aspects of the
work were supported by an End-stage chronic kidney disease is associated with striking excesses of cardiovascular
unrestricted educational grant from mortality, but it is uncertain to what extent renal function is related to risk of subsequent
GlaxoSmithKline (JD). The funding coronary heart disease (CHD) in apparently healthy adults. This study aims to quantify the
sources had no role in the study
design, data collection and analysis, association of markers of renal function with CHD risk in essentially general populations.
decision to publish, or preparation
of the manuscript.
Methods and Findings
Competing Interests: The authors
have declared that no competing Estimated glomerular filtration rate (eGFR) was calculated using standard prediction
interests exist.
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