原创力文档safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria a prospective multi-centre individual patient data analysis安全性和有效性的dihydroartemisinin-piperaquine恶性疟疾个别患者的前瞻性多中心数据分析.pdfVIP
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safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria a prospective multi-centre individual patient data analysis安全性和有效性的dihydroartemisinin-piperaquine恶性疟疾个别患者的前瞻性多中心数据分析
Safety and Efficacy of Dihydroartemisinin-Piperaquine in
Falciparum Malaria: A Prospective Multi-Centre
Individual Patient Data Analysis
1 1 6,7 7 4
Julien Zwang , Elizabeth A. Ashley , Corine Karema , Umberto D’Alessandro , Frank Smithuis , Grant
9 8 3,5,10 5 2
Dorsey , Bart Janssens , Mayfong Mayxay , Paul Newton , Pratap Singhasivanon , Kasia
Stepniewska2,3, Nicholas J. White2,3, Franc¸ois Nosten1,2,3*
1 Shoklo Malaria Research Unit, Mae Sot, Thailand, 2 Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, 3 Centre for Tropical Medicine, Nuffield
´ `
Department of Clinical Medicine, University of Oxford, CCVTM, Oxford, United Kingdom, 4 Medecins Sans Frontieres - Holland, Yangon, Myanmar, 5 Wellcome Trust –
Mahosot Hospital – Oxford Tropical Medicine Research Collaboration, Mahosot Hospital, Vientiane, Laos, 6 National Malaria Control Programme, Kigali, Rwanda, 7 Institute
´ `
of Tropical Medicine, Antwerp, Belgium, 8 Medecins Sans Frontieres- Belgium, Phnom Penh, Cambodia, 9 Department of Medicine, University of California San Francisco,
San Francisco, California, United States of America, 10 Department of Postgraduate Studies and Research, University of Health Sciences, Vientiane, Laos
Abstract
Background: The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new
artemisinin-based combination ther
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