原创力文档safety and immunogenicity of a recombinant plasmodium falciparum ama1 malaria vaccine adjuvanted with alhydrogel？, montanide isa 720 or as02安全性和免疫原性的重组与alhydrogel ama1恶性疟原虫疟疾疫苗佐剂的,或as02 montanide isa 720.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
safety and immunogenicity of a recombinant plasmodium falciparum ama1 malaria vaccine adjuvanted with alhydrogel？, montanide isa 720 or as02安全性和免疫原性的重组与alhydrogel ama1恶性疟原虫疟疾疫苗佐剂的,或as02 montanide isa 720
Safety and Immunogenicity of a Recombinant
Plasmodium falciparum AMA1 Malaria Vaccine
Adjuvanted with AlhydrogelTM, Montanide ISA 720 or
AS02
1 2 1 1 3 3
Meta Roestenberg *, Ed Remarque , Erik de Jonge , Rob Hermsen , Hildur Blythman , Odile Leroy ,
3 3 4 2 2
Egeruan Imoukhuede , Soren Jepsen , Opokua Ofori-Anyinam , Bart Faber , Clemens H. M. Kocken ,
2 2 1 1 1 4¤
Miranda Arnold , Vanessa Walraven , Karina Teelen , Will Roeffen , Quirijn de Mast , W. Ripley Ballou ,
4 4 ´ 5 1 2
Joe Cohen , Marie Claude Dubois , Stephane Ascarateil , Andre van der Ven , Alan Thomas , Robert
Sauerwein1
1 Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, 2 Biomedical Primate Research Centre, Rijswijk, The Netherlands, 3 European Malaria Vaccine
Initiative, Copenhagen, Denmark, 4 GlaxoSmithKline Biologicals, Rixensart, Belgium, 5 SEPPIC, Paris, France
Abstract
Background: Plasmodium falciparum Apical Membrane Antigen 1 (PfAMA1) is a candidate vaccine antigen expressed by
merozoites and sporozoites. It plays a key role in red blood cell and hepatocyte invasion that can be blocked by antibodies.
Methodology/Principal Findings: We assessed the safety and immunogenicity of recombinant PfAMA1 in a dose-
escalating, phase Ia trial. PfAMA1 FVO strain, produced in Pichia pastoris, was reconstitu
您可能关注的文档
- rnai-mediated silencing of paramyosin expression in trichinella spiralis results in impaired viability of the parasiternai-mediated paramyosin表达的沉默在旋毛虫结果受损的可行性的寄生虫.pdf
- rnf12 activates xist and is essential for x chromosome inactivationrnf12激活xist和x染色体失活是至关重要的.pdf
- robust models for optic flow coding in natural scenes inspired by insect biology鲁棒模型光学流编码在自然场景的灵感来自昆虫生物学.pdf
- robust time estimation reconciles views of the antiquity of placental mammals健壮的时间估计和解的古代胎盘类哺乳动物的观点.pdf
- robust signal processing in living cells强劲的信号处理在活细胞.pdf
- rock sparrow song reflects male age and reproductive success岩石麻雀之歌反映了男性的年龄和繁殖成功率.pdf
- robustness under functional constraint the genetic network for temporal expression in drosophila neurogenesis功能约束下的鲁棒性的遗传网络果蝇神经发生的时间表达.pdf
- rock art at the pleistoceneholocene boundary in eastern south america岩石艺术在南美东部pleistoceneholocene边界.pdf
- rna-interference knockdown of drosophila pigment dispersing factor in neuronal subsets the anatomical basis of a neuropeptide's circadian functionsrna干扰击倒的果蝇神经元子集的颜料分散因素神经肽的解剖学基础的生理功能.pdf
- rodent abundance dynamics and leptospirosis carriage in an area of hyper-endemicity in new caledonia啮齿动物丰度动力学和钩端螺旋体病马车在新喀里多尼亚hyper-endemicity的一个领域.pdf
- safety and immunogenicity of an hiv adenoviral vector boost after dna plasmid vaccine prime by route of administration a randomized clinical trial艾滋病毒的安全性和免疫原性adenoviral向量提高质粒dna疫苗'后给药途径一个随机临床试验.pdf
- safety and immunogenicity of boosting bcg vaccinated subjects with bcg comparison with boosting with a new tb vaccine, mva85a提高bcg接种疫苗的安全性和免疫原性主题与bcg比较增加一个新的结核病疫苗,mva85a.pdf
- safe from harm learned, instructed, and symbolic generalization pathways of human threat-avoidance免受伤害,指示,象征人类threat-avoidance的推广途径.pdf
- safety and immunogenicity following administration of a live, attenuated monovalent 2009 h1n1 influenza vaccine to children and adults in two randomized controlled trials安全性和免疫原性管理现场后,减单价2009 h1n1流感疫苗对儿童和成人在两个随机对照试验.pdf
- safety and immunogenicity of rsh28gst antigen in humans phase 1 randomized clinical study of a vaccine candidate against urinary schistosomiasisrsh28gst的安全性和免疫原性抗原在人类第一阶段的随机临床研究对尿路血吸虫病的候选疫苗.pdf
- safety and immunogenicity of an ama1 malaria vaccine in malian children results of a phase 1 randomized controlled trialama1疟疾疫苗的安全性和免疫原性马里孩子第一阶段随机对照试验的结果.pdf
- safety and immunogenicity of the candidate tuberculosis vaccine mva85a in west africa候选结核病疫苗的安全性和免疫原性mva85a在西非.pdf
- safety and immunogenicity of the malaria vaccine candidate msp3 long synthetic peptide in 12–24 months-old burkinabe children疟疾疫苗的安全性和免疫原性候选人msp3长12 - 24仅有几个月的国内儿童的合成肽.pdf
- safety and immunogenicity of an hiv-1 gag dna vaccine with or without il-12 andor il-15 plasmid cytokine adjuvant in healthy, hiv-1 uninfected adultshiv - 1的安全性和免疫原性呕吐dna疫苗可以有或没有il - 12和或il-15质粒在健康细胞因子佐剂,hiv - 1感染的成年人.pdf
- safety and immunogenicity of therapeutic dna vaccination in individuals treated with antiretroviral therapy during acuteearly hiv-1 infection治疗性dna疫苗的安全性和免疫原性个人接受抗逆转录病毒疗法在acuteearly hiv - 1感染.pdf
文档评论（0）