原创力文档seroprevalence of fecal-oral transmitted hepatitis a and e virus antibodies in burkina fasoseroprevalence粪口传播甲型和戊型肝炎病毒抗体在布基纳法索.pdfVIP
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seroprevalence of fecal-oral transmitted hepatitis a and e virus antibodies in burkina fasoseroprevalence粪口传播甲型和戊型肝炎病毒抗体在布基纳法索
Seroprevalence of Fecal-Oral Transmitted Hepatitis A
and E Virus Antibodies in Burkina Faso
´ 1 2 ´ ´ 3 3 ´ 1
Kuan Abdoulaye Traore , Hortense Rouamba , Yacouba Nebie , Mahamadou Sanou , Alfred S. Traore ,
1 . 4,5 .
Nicolas Barro * , Pierre Roques *
´
1 Centre de Recherche en Sciences Biologique Alimentaire Nutritionnelles (CRSBAN), Universite de Ouagadougou, Ouagadougou, Burkina Faso, 2 Centre National de
´
Transfusion Sanguine, Ouagadougou, Burkina Faso, 3 Centre medical de Samandin, Ouagadougou, Burkina Faso, 4 Division of Immuno-Virologie, Institute of Emerging
`
Diseases and Innovative Therapies, Commissariat a l’Energie Atomique (CEA), Fontenay-aux-Roses, France, 5 Unite Mixte de Recherche E1, University Paris Sud 11, Orsay,
France
Abstract
Hepatitis A virus (HAV) and hepatitis E virus (HEV) infections occur chiefly as a result of unhygienic conditions. The purpose
of this study was to assess the seroprevalence of antibodies to both viruses in central Burkina Faso in the absence of
a recorded hepatitis epidemic. Serum samples from 178 blood donors (131 males and 47 females) and from 189 pregnant
women were collected from November 2010 to March 2012, at blood banks and medical centers in Burkina Faso. An
immunochromatography test was used to screen for Anti-HAV IgM and IgG in a subgroup of 91 blood donors and 100
pregnant women. The seroprevalence of anti-HAV IgG was 14.3% [CI95, 7.1–21.
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