原创力文档somatic ‘soluble’ adenylyl cyclase isoforms are unaffected in sacytm1lexsacytm1lex ‘knockout’ mice体可溶性的腺苷酸环化酶亚型在sacytm1lexsacytm1lex影响基因敲除的小鼠.pdfVIP
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somatic ‘soluble’ adenylyl cyclase isoforms are unaffected in sacytm1lexsacytm1lex ‘knockout’ mice体可溶性的腺苷酸环化酶亚型在sacytm1lexsacytm1lex影响基因敲除的小鼠
Somatic ‘Soluble’ Adenylyl Cyclase Isoforms Are
Unaffected in Sacytm1Lex/Sacytm1Lex ‘Knockout’ Mice
Jeanne Farrell., Lavoisier Ramos., Martin Tresguerres, Margarita Kamenetsky, Lonny R. Levin*, Jochen
Buck
Department of Pharmacology, Weill Medical College of Cornell University, New York, New York, United States of America
Abstract
Background: Mammalian Soluble adenylyl cyclase (sAC, Adcy10, or Sacy) represents a source of the second messenger
cAMP distinct from the widely studied, G protein-regulated transmembrane adenylyl cyclases. Genetic de
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