species shifts in the anopheles gambiae complex do llins successfully control anopheles arabiensis冈比亚疟蚊的物种变化复杂做卫疟arabiensis成功控制.pdfVIP

Species Shifts in the Anopheles gambiae Complex: Do LLINs Successfully Control Anopheles arabiensis ? Jovin Kitau1,4*, Richard M. Oxborough1,3,4, Patrick K. Tungu2,4, Johnson Matowo1,4, Robert C. Malima2,4, 2,4,5 3 1,4 3,4 Stephen M. Magesa , Jane Bruce , Franklin W. Mosha , Mark W. Rowland 1 Kilimanjaro Christian Medical College, Tumaini University, Moshi, Tanzania, 2 National Institute for Medical Research, Amani Medical Research Centre, Muheza, Tanzania, 3 London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom, 4 Pan-African Malaria Vector Research Consortium, Moshi and Muheza- Tanzania, Cotonou-Benin, London School of Hygiene and Tropical Medicine, United Kingdom, 5 RTI International, Centre for Strategic Malaria Solutions, Global Health Group, Nairobi, Kenya Abstract Introduction: High coverage of conventional and long-lasting insecticide treated nets (ITNs and LLINs) in parts of E Africa are associated with reductions in local malaria burdens. Shifts in malaria vector species ratio have coincided with the scale- up suggesting that some species are being controlled by ITNs/LLINs better than others. Methods: Between 2005–2006 six experimental hut trials of ITNs and LLINs were conducted in parallel at two field stations in northeastern Tanzania; the first station was in Lower Moshi Rice Irrigation Zone, an area where An. arabiensis predominates, and the second was in coastal Muheza, where An. gambiae and An. funestus predominate. Five pyrethroids and one carbamate insecticide were evaluated on nets in terms of insecticide-induced mortality, blood-feeding inhibition and exiting rates. Results: In the experimental hut trials mortality of An. arabien