鹿丹通督片对大鼠实验性腰神经根炎的影响(Effect of ludantongdu tablet on experimental rats with lumbar nerve root inflammation).docVIP
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鹿丹通督片对大鼠实验性腰神经根炎的影响(Effect of ludantongdu tablet on experimental rats with lumbar nerve root inflammation)
鹿丹通督片对大鼠实验性腰神经根炎的影响(Effect of ludantongdu tablet on experimental rats with lumbar nerve root inflammation)
Effect of ludantongdu tablet on experimental rats with lumbar nerve root inflammation
Update Date: 2009-07-09 Click: Shen Lin, Gao Lan, Xie Jing, Li Tongsheng
Methods 96 rats were randomly divided into high dose group, low dose group, ibuprofen group and saline group. The establishment of the fifth lumbar nerve root inflammation in the rat model by chemical stimulation method, observation of rats lower limb nerve function and local pathological changes, and anterior tibial muscle monoamine neurotransmitter of motor nerve conduction velocity and brain norepinephrine (NE), 5- 5- (5-HT), serotonin hydroxyindole acetic acid (5-HIAA) and beta endorphin (beta -EP) determination. The results show that ludantongdu tablet can reduce rats inflammatory area of nerve root edema, protect the structure of myelin sheath; metabolism can modulate neurotransmitter, decrease NE, 5-HT and 5-HIAA in the brain tissue of rats, and increase the content of beta -EP; promote rat model of limb gait, tactile and electrophysiological function recovery.
Application of neurotransmitter electrophysiological experiments of key words and nerve root inflammation / TCM therapy ludantongdu tablet / therapy
CLC number: R289.5; R745.4 document identifier: A
Article number: 1001-6015 (2000) 03-0003-03
THE, INFLUENCE, OF, LUDAN, TONGDU, PIAN, ON, EXPERIMENTAL, LUMBAR,, RADICULITIS, IN, RATS
Shen, Lin, Shen Lin, Gao, Lan, Gao Lan, Xie, Jing, Xie Jing, et, Al
Xiehe, Hospital, Affiliated, to, Tongji, Medical, University, Wuhan 43002
Ninety-six rats were randomly divided into four groups, which were treated by low and high doses of LUDAN TONGDU PIAN (LDTP TCD, tablets for dredging the Du Channel), ibuprofen (I) and saline (S), respectively. Rat models of L5 radiculitis were made by chemical irritation, the neural function and the local pathological changes of the lower limbs of the rat models were observe
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