原创力文档afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine传入信号从acid-challenged鼠胃是抑制胃酸消除由lafutidine增强.pdfVIP
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afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine传入信号从acid-challenged鼠胃是抑制胃酸消除由lafutidine增强
BMC Gastroenterology BioMed Central
Research article Open Access
Afferent signalling from the acid-challenged rat stomach is inhibited
and gastric acid elimination is enhanced by lafutidine
1 2 1
Martin E Edelsbrunner , Motoko Nakano and Peter Holzer*
Address: 1Research Unit of Translational Neurogastroenterology, Institute of Experimental and Clinical Pharmacology, Medical University of Graz,
Universitätsplatz 4, A-8010 Graz, Austria and 2Optimal Medication Research Laboratory, Tokushima Research Center, Taiho Pharmaceutical Co.
Ltd., 224-2 Ebisuno, Hiraishi, Kawauchi-cho, Tokushima-City, 771-0194 Japan
Email: Martin E Edelsbrunner - ma.edelsbrunner@medunigraz.at; Motoko Nakano - moto-nakano@taiho.co.jp;
Peter Holzer* - peter.holzer@medunigraz.at
* Corresponding author
Published: 2 June 2009 Received: 4 March 2009
Accepted: 2 June 2009
BMC Gastroenterology 2009, 9:40 doi:10.1186/1471-230X-9-40
This article is available from: /1471-230X/9/40
© 2009 Edelsbrunner et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Lafutidine is a histamine H receptor antagonist, the gastroprotective effect of which
2
is related
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