alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array可变剪接和微分在结肠癌基因表达检测全基因组外显子数组.pdfVIP

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alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array可变剪接和微分在结肠癌基因表达检测全基因组外显子数组.pdf

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alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array可变剪接和微分在结肠癌基因表达检测全基因组外显子数组

BMC Genomics BioMed Central Research article Open Access Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array Paul J Gardina, Tyson A Clark, Brian Shimada, Michelle K Staples, Qing Yang, James Veitch, Anthony Schweitzer, Tarif Awad, Charles Sugnet, Suzanne Dee, Christopher Davies, Alan Williams and Yaron Turpaz* Address: Affymetrix, Inc., 3420 Central Expressway, Santa Clara, CA 95051, USA Email: Paul J Gardina - Paul_Gardina@A; Tyson A Clark - tyson_clark@; Brian Shimada - Brian_Shimada@; Michelle K Staples - Michelle_Staples@A; Qing Yang - Qing_Yang@; James Veitch - Jim_Veitch@A; Anthony Schweitzer - Anthony_Schweitzer@A; Tarif Awad - tarif_awad@; Charles Sugnet - Charles_Sugnet@A; Suzanne Dee - Suzanne_Dee@; Christopher Davies - christopher_davies@; Alan Williams - Alan_Williams@; Yaron Turpaz* - yaron_turpaz@ * Corresponding author Published: 27 December 2006 Received: 04 October 2006 Accepted: 27 December 2006 BMC Genomics 2006, 7:325 doi:10.1186/1471-2164-7-325 This article is available from: /1471-2164/7/325 © 2006 Gardina et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Alternative splicing is a mechanism for increasing protein diversity by excluding or including exons during post