原创力文档analysis of feedback loops and robustness in network evolution based on boolean models反馈回路和鲁棒性的分析基于布尔网络演化模型.pdfVIP
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analysis of feedback loops and robustness in network evolution based on boolean models反馈回路和鲁棒性的分析基于布尔网络演化模型
BMC Bioinformatics BioMed Central
Research article Open Access
Analysis of feedback loops and robustness in network evolution
based on Boolean models
Yung-Keun Kwon and Kwang-Hyun Cho*
Address: Department of Bio and Brain Engineering and KI for the BioCentury, Korea Advanced Institute of Science and Technology, 335
Gwahangno, Yuseong-gu, Daejeon, 305-701, Republic of Korea
Email: Yung-Keun Kwon - kwon@soar.snu.ac.kr; Kwang-Hyun Cho* - ckh@kaist.ac.kr
* Corresponding author
Published: 7 November 2007 Received: 30 April 2007
Accepted: 7 November 2007
BMC Bioinformatics 2007, 8:430 doi:10.1186/1471-2105-8-430
This article is available from: /1471-2105/8/430
© 2007 Kwon and Cho; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Many biological networks such as protein-protein interaction networks, signaling
networks, and metabolic networks have topological characteristics of a scale-free degree
distribution. Preferential attachment has been considered as the most plausible evolutionary
growth model to explain this topological property. Although various studies have been undertaken
to investigate the structural characteristics of a network obtained using this growth model, its
dynamical characteristics
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