原创力文档antibacterial activity of some selected medicinal plants of pakistan巴基斯坦的一些选定的药用植物的抗菌活性.pdfVIP
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antibacterial activity of some selected medicinal plants of pakistan巴基斯坦的一些选定的药用植物的抗菌活性
Bibi et al. BMC Complementary and Alternative Medicine 2011, 11:52
/1472-6882/11/52
RESEARCH ARTICLE Open Access
Antibacterial activity of some selected medicinal
plants of Pakistan
1 1 1 2*
Yamin Bibi , Sobia Nisa , Fayyaz M Chaudhary and Muhammad Zia
Abstract
Background: Screening of the ethnobotenical plants is a pre-requisite to evaluate their therapeutic potential and it
can lead to the isolation of new bioactive compounds.
Methods: The crude extracts and fractions of six medicinal important plants (Arisaema flavum, Debregeasia
salicifolia, Carissa opaca, Pistacia integerrima, Aesculus indica, and Toona ciliata) were tested against three Gram
positive and two Gram negative ATCC bacterial species using the agar well diffusion method.
Results: The crude extract of P. integerrima and A. indica were active against all tested bacterial strains (12-23 mm
zone of inhibition). Other four plant’s crude extracts (Arisaema flavum, Debregeasia salicifolia, Carissa opaca, and
Toona ciliata) were active against different bacterial strains. The crude extracts showed varying level of bactericidal
activity. The aqueous fractions of A. indica and P. integerrima crude extract showed maximum activity (19.66 and 16
mm, respectively) against B. subtilis, while the chloroform fractions of T. ciliata and D. salicifolia presented good
antibacterial activities (13-17 mm zone of inhibition) against all the bacterial cultures tested.
Conclusion: The methanol fraction of Pistacia integerrima, chloroform fractions of Debregeasia salicifolia Toona
ciliata and aqueous fraction of Aesculus indica are suitable candidates for the development of novel antibacterial
compounds.
Background
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