atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout miceatm杂合的缺陷提高乳房癌中p53杂合的基因敲除小鼠的发展.pdfVIP

Available online /content/7/1/R164 Vol 7 No 1 Open Access Research article Atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout mice 1 2 1 1,3 1 Seiichi Umesako , Kae Fujisawa , Sayoko Iiga , Nobuko Mori , Masahiro Takahashi , Doo- 1 4 5 6 7 Pyo Hong , Chang-Woo Song , Satomi Haga , Syunsuke Imai , Otsura Niwa and Masaaki Okumoto1,3 1Graduate school of Agriculture and Biological Sciences, Osaka Prefecture University, Osaka, Japan 2Research Institute of New Medicines, Shionogi Pharmaceutical Co., Osaka, Japan 3Research Institute for Advanced Science and Technology, Osaka Prefecture University, Osaka, Japan 4Korea Research Institute of Chemical Technology, Taejon, Korea 5Department of Anatomy, Nara Medical University, Nara, Japan 6Nara Prefecture Institute for Hygiene and Environment, Nara, Japan 7Radiation Biology Center, Kyoto University, Kyoto, Japan Corresponding author: Masaaki Okumoto, okumoto@riast.osakafu-u.ac.jp Received: 27 Jul 2004 Revisions requested: 17 Sep 2004 Revisions received: 15 Oct 2004 Accepted: 15 Oct 2004 Published: 10 Dec 2004 Breast Cancer Res 2005, 7:R164-R170 (DOI 10.1186/bcr968) /content/7/1/R164 © 2004 Umesako et al., licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/ 2.0,) which per