aurora-a overexpression enhances cell-aggregation of ha-ras transformants through the mekerk signaling pathwayaurora-a超表达增强的细胞集合ha-ras转化株mekerk信号通路.pdfVIP

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aurora-a overexpression enhances cell-aggregation of ha-ras transformants through the mekerk signaling pathwayaurora-a超表达增强的细胞集合ha-ras转化株mekerk信号通路.pdf

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aurora-a overexpression enhances cell-aggregation of ha-ras transformants through the mekerk signaling pathwayaurora-a超表达增强的细胞集合ha-ras转化株mekerk信号通路

BMC Cancer BioMed Central Research article Open Access Aurora-A overexpression enhances cell-aggregation of Ha-ras transformants through the MEK/ERK signaling pathway 1 2 3 Ya-Shih Tseng , Jenq-Chang Lee , Chi-Ying F Huang and Hsiao-Sheng Liu*4,5 Address: 1Department of Medical Technology, Chung Hwa University of Medical technology, Tainan, Taiwan, 2Department of Surgery, College of Medicine, National Cheng Kung University Hospital, Tainan, Taiwan, 3Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, 4Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan and 5Center for Gene Regulation and Signal Transduction Research, National Cheng Kung University, Tainan, Taiwan Email: Ya-Shih Tseng - shih415@.tw; Jenq-Chang Lee - leejc@.tw; Chi-Ying F Huang - cyhuang5@.tw; Hsiao-Sheng Liu* - a713@.tw * Corresponding author Published: 12 December 2009 Received: 22 December 2008 Accepted: 12 December 2009 BMC Cancer 2009, 9:435 doi:10.1186/1471-2407-9-435 This article is available from: /1471-2407/9/435 © 2009 Tseng et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Overexpression of Aurora-A and mutant Ras (RasV12) together has been detected