ayums an algorithm for completely automatic quantitation based on lc-msms proteome data and its application to the analysis of signal transductionayums算法基于lc-msms的全自动定量蛋白质组数据及其应用的分析信号转导.pdfVIP

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ayums an algorithm for completely automatic quantitation based on lc-msms proteome data and its application to the analysis of signal transductionayums算法基于lc-msms的全自动定量蛋白质组数据及其应用的分析信号转导.pdf

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ayums an algorithm for completely automatic quantitation based on lc-msms proteome data and its application to the analysis of signal transductionayums算法基于lc-msms的全自动定量蛋白质组数据及其应用的分析信号转导

BMC Bioinformatics BioMed Central Software Open Access AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction † † † Ayumu Saito* , Masao Nagasaki , Masaaki Oyama , Hiroko Kozuka-Hata, Kentaro Semba, Sumio Sugano, Tadashi Yamamoto and Satoru Miyano Address: The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan Email: Ayumu Saito* - s-ayumu@ims.u-tokyo.ac.jp; Masao Nagasaki - masao@ims.u-tokyo.ac.jp; Masaaki Oyama - moyama@ims.u-tokyo.ac.jp; Hiroko Kozuka-Hata - hata@ims.u-tokyo.ac.jp; Kentaro Semba - ksemba@ims.u-tokyo.ac.jp; Sumio Sugano - ssugano@ims.u-tokyo.ac.jp; Tadashi Yamamoto - tyamamot@ims.u-tokyo.ac.jp; Satoru Miyano - miyano@ims.u-tokyo.ac.jp * Corresponding author †Equal contributors Published: 18 January 2007 Received: 16 August 2006 Accepted: 18 January 2007 BMC Bioinformatics 2007, 8:15 doi:10.1186/1471-2105-8-15 This article is available from: /1471-2105/8/15 © 2007 Saito et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Comprehensive description of the behavior of cellular components in a quantitative manner is essential for systematic