higher urinary sodium, a proxy for intake, is associated with increased calcium excretion and lower hip bone density in healthy young women with lower calcium intakes高尿钠、代表的摄入,增加钙的排泄,降低髋部骨密度与低钙摄入健康的年轻女性.pdfVIP

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higher urinary sodium, a proxy for intake, is associated with increased calcium excretion and lower hip bone density in healthy young women with lower calcium intakes高尿钠、代表的摄入,增加钙的排泄,降低髋部骨密度与低钙摄入健康的年轻女性.pdf

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higher urinary sodium, a proxy for intake, is associated with increased calcium excretion and lower hip bone density in healthy young women with lower calcium intakes高尿钠、代表的摄入,增加钙的排泄,降低髋部骨密度与低钙摄入健康的年轻女性

Nutrients 2011, 3, 951-961; doi:10.3390/nu3110951 OPEN ACCESS nutrients ISSN 2072-6643 /journal/nutrients Article Higher Urinary Sodium, a Proxy for Intake, Is Associated with Increased Calcium Excretion and Lower Hip Bone Density in Healthy Young Women with Lower Calcium Intakes Jennifer L. Bedford 1 and Susan I. Barr 2,* 1 Diabetes Education Centre, Ross Memorial Hospital, 10 Angeline St N, Lindsay, Ontario K9V 4M8, Canada; E-Mail: jennifer.lynn.bedford@ 2 University of British Columbia, 2205 East Mall, Vancouver, BC V6T 1Z4, Canada * Author to whom correspondence should be addressed; E-Mail: susan.barr@ubc.ca; Tel.: +1-604-822-6766; Fax: +1-604-822-5143. Received: 4 October 2011; in revised form: 1 November 2011 / Accepted: 3 November 2011/ Published: 10 November 2011 Abstract: We assessed 24-h urinary sodium (Na) and its relationship with urinary calcium (Ca) and areal bone mineral density (aBMD) at the whole body, lumbar spine and total hip in a cross-sectional study. 102 healthy non-obese women completed timed 24-h urine collections which were analyzed for Na and Ca. Dietary intakes were estimated using a validated food frequency questionnaire. Participants were grouped as those with lower vs. higher calcium intake by median split (506 mg/1000 kcal). Dietary Na intake correlated with 24-h urinary loss. Urinary Na correlated positively with urinary Ca for all participants (r = 0.29, p 0.01) and among those with lower (r = 0.37, p 0.01) but not hig