原创力文档hiv-free survival and morbidity among formula-fed infants in a prevention of mother-to-child transmission of hiv program in rural haiti免于感染艾滋病病毒的生存和发病率在人工喂养的宝宝预防母婴传播艾滋病毒的程序在海地的农村.pdfVIP
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hiv-free survival and morbidity among formula-fed infants in a prevention of mother-to-child transmission of hiv program in rural haiti免于感染艾滋病病毒的生存和发病率在人工喂养的宝宝预防母婴传播艾滋病毒的程序在海地的农村
Ivers et al. AIDS Research and Therapy 2011, 8:37
/content/8/1/37
RESEARCH Open Access
HIV-free survival and morbidity among formula-
fed infants in a prevention of mother-to-child
transmission of HIV program in rural Haiti
1,2,3* 2 4 5 2
Louise C Ivers , Sasha C Appleton , Bingxia Wang , J Gregory Jerome , Kimberly A Cullen and
Mary C Smith Fawzi2,3
Abstract
Background: Partners In Health (PIH) works with the Ministry of Health to provide comprehensive health services
in Haiti. Between 1994 and 2009, PIH recommended exclusive formula feeding in the prevention of mother-to-
child transmission (PMTCT) of HIV program and provided support to implement this strategy. We conducted this
study to assess HIV-free survival and prevalence of diarrhea and malnutrition among infants in our PMTCT program
in rural Haiti where exclusive formula feeding was supported.
Methods: We reviewed medical charts of PMTCT mother-infant pairs at PIH between November 2004 and August
2006 through a retrospective longitudinal study and cross-sectional survey. We performed household surveys for
each pair and at control households matched by infant’s age and gender.
Results: 254 mother-infant pairs were included. 15.3% of infants were low birth weight; most births occurred at
home (68.8%). 55.9% of households had no latrine; food insecurity was high (mean score of 18; scale 0-27, SD =
5.3). HIV-free survival at 18 months was 90.6%. Within the cohort, 9 children (3.5%) were HIV-infected and 17 (6.7%)
died. Community controls were more likely to be breastfed (P = 0.003) and more likely to introduce food early (P =
0.003) than PMTCT-program households. There was no difference in moderate malnutrition (Z score ≤ 2
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