hla class ii dr and dq genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of latvian childrenhla二类博士和dq基因型和单体型与风湿热在临床上均匀患者人群拉脱维亚的孩子.pdfVIP

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hla class ii dr and dq genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of latvian childrenhla二类博士和dq基因型和单体型与风湿热在临床上均匀患者人群拉脱维亚的孩子.pdf

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hla class ii dr and dq genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of latvian childrenhla二类博士和dq基因型和单体型与风湿热在临床上均匀患者人群拉脱维亚的孩子

Available online /content/9/3/R58 Vol 9 No 3 Open Access Research article HLA class II DR and DQ genotypes and haplotypes associated with rheumatic fever among a clinically homogeneous patient population of Latvian children 1 2 1 2 3 Valda Stanevicha , Jelena Eglite , Dace Zavadska , Arturs Sochnevs , Ruta Shantere and Dace Gardovska1 1Department of Pediatrics, Riga Stradins University, Vienîbas gatve 45, Riga, LV1004, Latvia 2Department of Imunology, Riga Stradins University, Dzirciema iela 16, Riga, LV1007, Latvia 3Children Clinical University Hospital, Vienîbas gatve 45, Riga, LV1004, Latvia Corresponding author: Valda Stanevicha, valda.stanevicha@one.lv Received: 15 Feb 2007 Revisions requested: 23 Mar 2007 Revisions received: 10 Apr 2007 Accepted: 10 Jun 2007 Published: 10 Jun 2007 Arthritis Research Therapy 2007, 9:R58 (doi:10.1186/ar2216) This article is online at: /content/9/3/R58 © 2007 Stanevicha et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract The HLA system is being paid more and more attention because DQA1 genotypes, *07/*0201 and *01/*0501 were frequently it is very significant in polymorphous immunological reactions. detected; these also occurred significantly often in the MVL Several studies have suggested that genetic susceptibility to group. The genotype *07/*0201 was fre