原创力文档- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
identifying protein-coding genes in genomic sequences识别蛋白质编码基因在基因组序列
Review
IIddeennttiiffyyiinngg pprrootteeiinn--ccooddiinngg ggeenneess iinn ggeennoommiicc sseeqquueenncceess
† ‡ §
Jennifer Harrow*, Alinda Nagy , Alexandre Reymond , Tyler Alioto ,
† ¶ §
Laszlo Patthy , Stylianos E Antonarakis and Roderic Guigó
Addresses: *Wellcome Trust Sanger Institute, Wellcome Trust Campus, Hinxton, Cambridge CB10 1SA, UK. †Institute of Enzymology,
Biological Research Center, Hungarian Academy of Sciences, H-1113 Budapest, Hungary. ‡Center for Integrative Genomics, Genopode
Building, University of Lausanne, CH-1015 Lausanne, Switzerland. §Centre de Regulació Genòmica, Institut Municipal d’Investigació Mèdica,
Universitat Pompeu Fabra, E-08003 Barcelona, Catalonia, Spain. ¶Department of Genetic Medicine and Development, University of Geneva
Medical School and University Hospitals of Geneva, Geneva 1211, Switzerland.
Correspondence: Roderic Guigó: Email: roderic.guigo@crg.es
Published: 30 January 2009
Genome BBiioollooggyy 2009, 1100::201 (doi:10.1186/gb-2009-10-1-201)
The electronic version of this article is the complete one and can be
found online at /2009/10/1/201
© 2009 BioMed Central Ltd
AAbbssttrraacctt
The vast majority of the biology of a newly sequenced genome is inferred from the set of
encoded proteins. Predicting this set is therefore invariably the first step after the completion of
the genome DNA sequence. Here we review the main computational pipelines used to generate
the human reference protein-coding gene sets.
The genome sequence is an organism’s blueprint: the set of
您可能关注的文档
- hippocampal volume reduction in children with chromosome 22q11.2 deletion syndrome is associated with cognitive impairment海马体积的减少染色体22 q11.2删除综合症患儿与认知障碍相关.pdf
- histidine protein kinases key signal transducers outside the animal kingdom组氨酸蛋白激酶关键信号传感器在动物王国之外.pdf
- hispanic latin america, spain and the spanish-speaking caribbean a rich source of reference material for public health, epidemiology and tropical medicine西班牙和西班牙语裔拉丁美洲,加勒比地区丰富的参考资料来源公共卫生、流行病学和热带医学.pdf
- high-throughput sequencing identifies stat3 as the dna-associated factor for p53-nf-κb-complex-dependent gene expression in human heart failure高通量测序识别stat3作为p53-nf-κb-complex-dependent dna-associated因子基因表达在人类心脏衰竭.pdf
- hill-climbing search and diversification within an evolutionary approach to protein structure prediction爬山搜索和多样化在进化的蛋白质结构预测方法.pdf
- histological and immunohistochemical features of the spleen in persistent polyclonal b-cell lymphocytosis closely mimic splenic b-cell lymphoma脾脏的组织学和免疫组织化学特性持续多克隆b细胞淋巴球增多密切模仿脾脏b细胞淋巴瘤.pdf
- histone deacetylase inhibitors advancing therapeutic strategies in hematological and solid malignancies组蛋白脱乙酰酶抑制剂推进在血液和固体恶性肿瘤的治疗策略.pdf
- histological spectrum of pulmonary manifestations in kidney transplant recipients on sirolimus inclusive immunosuppressive regimens组织学的肺部表现在肾移植受者西罗莫司的免疫抑制方案.pdf
- histogenesis of retinal dysplasia in trisomy 13组织发生视网膜发育异常的三倍体13.pdf
- histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in skg mice组蛋白脱乙酰酶抑制改变树突细胞承担耐受性表型和改善关节炎小鼠热议.pdf
- identification of small molecule inhibitors of clostridium perfringens ε-toxin cytotoxicity using a cell-based high-throughput screen确定小分子抑制剂的梭状芽胞杆菌perfringensε-toxin使用细胞筛选细胞毒性.pdf
- immediate effects of acupuncture on biceps brachii muscle function in healthy and post-stroke subjects立即针灸对肱二头肌肌肉功能的影响在健康和中风后科目.pdf
- illustrating risk difference and number needed to treat from a randomized controlled trial of spinal manipulation for cervicogenic headache说明风险差异和数量需要治疗的随机对照试验的脊髓操纵cervicogenic头痛.pdf
- impact of the introduction of biofuel in the transportation sector in indonesia的影响引入生物燃料在运输部门在印尼.pdf
- impact of ureidocarboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to pseudomonas aeruginosaureidocarboxypenicillin阻力对与机械通气相关肺炎的预后的影响由于铜绿假单胞菌.pdf
- implementation of an evidence-based sepsis program in the intensive care unit evident or not实施以证据为基础的脓毒症项目的重症监护室明显与否.pdf
- impact of delayed admission to intensive care units on mortality of critically ill patients a cohort study延迟的影响进入重症监护病房危重病人死亡率的队列研究.pdf
- identification of ciliated sensory neuron-expressed genes in caenorhabditis elegans using targeted pull-down of poly(a) tails纤毛感官鉴定neuron-expressed基因在秀丽隐杆线虫使用保利(a)的目标下拉尾巴.pdf
- implementation of the cmos mems condenser microphone with corrugated metal diaphragm and silicon back-plate实现cmos mems电容式传声器波纹金属薄膜和硅后松.pdf
- impact of accessory gene regulator (agr) dysfunction on vancomycin pharmacodynamics among canadian community and health-care associated methicillin-resistant staphylococcus aureus附属基因的影响调节器(agr)功能障碍万古霉素药效学在加拿大社区和卫生保健相关的耐甲氧西林金黄色葡萄球菌.pdf
文档评论（0）