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histogenesis of retinal dysplasia in trisomy 13组织发生视网膜发育异常的三倍体13
Diagnostic Pathology BioMed Central
Case Report Open Access
Histogenesis of retinal dysplasia in trisomy 13
1 2 1
Ada Chan , Satyan Lakshminrusimha , Reid Heffner and Federico Gonzalez-
Fernandez*3
Address: 1Department of Pathology, State University of New York, Buffalo, New York, USA, 2Department of Pediatrics, State University of New
York, Buffalo, New York, USA and 3Ross Eye Institute and departments of Ophthalmology, Pathology, Biochemistry, State University of New York,
Medical Research Service, Veterans Affairs Medical Center, Buffalo, New York, USA
Email: Ada Chan - adachan@; Satyan Lakshminrusimha - slakshmi@; Reid Heffner - rheffner@;
Federico Gonzalez-Fernandez* - fg23@
* Corresponding author
Published: 18 December 2007 Received: 6 July 2007
Accepted: 18 December 2007
Diagnostic Pathology 2007, 2:48 doi:10.1186/1746-1596-2-48
This article is available from: /content/2/1/48
© 2007 Chan et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Although often associated with holoprosencephaly, little detail of the
histopathology of cyclopia is available. Here, we describe the ocular findings in a case of trisomy 13
to better understand
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