monitoring the depth of anaesthesia监测麻醉深度.pdfVIP

Sensors 2010, 10, 10896-10935; doi:10.3390/s101210896 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Review Monitoring the Depth of Anaesthesia Bojan Musizza 1 and Samo Ribaric 2,* 1 Department of Systems and Control, Jožef Stefan Institute/Jamova 39, SI-1000 Ljubljana, Slovenia; E-Mail: bojan.musizza@ijs.si 2 Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana/Zaloška 4, SI-1000 Ljubljana, Slovenia * Author to whom correspondence should be addressed; E-Mail: samo.ribaric@mf.uni-lj.si; Tel.: +386-1-543-70-53; Fax: +386-543-70-21. Received: 1 September 2010; in revised form: 29 September 2010 / Accepted: 22 November 2010 / Published: 3 December 2010 Abstract: One of the current challenges in medicine is monitoring the patients’ depth of general anaesthesia (DGA). Accurate assessment of the depth of anaesthesia contributes to tailoring drug administration to the individual patient, thus preventing awareness or excessive anaesthetic depth and improving patients’ outcomes. In the past decade, there has been a significant increase in the number of studies on the development, comparison and validation of commercial devices that estimate the DGA by analyzing electrical activity of the brain (i.e., evoked potentials or brain waves). In this paper we review the most frequently used sensors and mathematical methods for monitoring the DGA, their validation in clinical practice and discuss the central question of whether t