mortality and morbidity study of petrochemical employees in a polluted site死亡率和发病率的研究石化员工在一个被污染的网站.pdfVIP

Pasetto et al. Environmental Health 2012, 11:34 /content/11/1/34 RESEARCH Open Access Mortality and morbidity study of petrochemical employees in a polluted site 1* 1 2 3 3 Roberto Pasetto , Amerigo Zona , Roberta Pirastu , Achille Cernigliaro , Gabriella Dardanoni , Sebastiano Pollina Addario3, Salvatore Scondotto3 and Pietro Comba1 Abstract Background: The area of Gela was included among the 57 Italian polluted sites of national interest for environmental remediation because of its widespread contamination from a petrochemical complex. The present study investigates mortality and morbidity of the cohort of Gela petrochemical workers with the aim of disentangling occupational from residential risk. Methods: Mortality was assessed for 5,627 men hired from 1960, year of the plant start-up, to 1993; it was followed up for vital status in the period 1960–2002. Morbidity was analysed for 5,431 workers neither dead nor lost to follow-up from 1960 to 2001 and was based on Hospital Discharge Records in the period 2001–2006. The work experience was classified in terms of job categories such as blue collars, white collars, and both – workers who shifted from blue to white collar (95%) or vice versa. An ad hoc mobility model was applied to define qualitative categories of residence in Gela, as residents and commuters. Standardized Mortality Ratios (SMRs) and Mortality Rate Ratios (MRRs) were computed, the latter by using a Poisson regression model. Morbidity was analyzed in terms of Hospital Discharge Odds Ratios (HDORs) through a logistic regression model. While performing the internal comparisons, white collars was the reference category for the job analysis, and commuters was the reference catego