intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast a case report and review of the literature的异位乳腺组织导管内乳头状瘤患者腋窝淋巴结的前一个侧乳腺导管内乳头状瘤的病例报告和文献回顾.pdfVIP

Dzodic et al. Diagnostic Pathology 2010, 5:17 /content/5/1/17 CASE REPORT Open Access Intraductal papilloma of ectopic breast tissue in axillary lymph node of a patient with a previous intraductal papilloma of ipsilateral breast: a case report and review of the literature 1 1,2* 3 4 1 1 Radan Dzodic , Boban Stanojevic , Vladimir Saenko , Masahiro Nakashima , Ivan Markovic , Gordana Pupic , 1 1 2 2,3 Marko Buta , Momcilo Inic , Tatiana Rogounovitch , Shunichi Yamashita Abstract The presence of ectopic breast tissue in axillary lymph nodes (ALN) is a benign condition that must be differen- tiated from primary or metastatic carcinoma. Here we report a patient who underwent excision of enlarged ALN 10 years after she had received surgical treatment of ipsilateral breast for an intracystic intraductal papilloma (IDP). Histological examination of the removed ALN revealed that the proliferative lesion consisted of papillary and tubu- lar structures lined by luminal cuboidal cells and a distinct outer layer of myoepithelial cells resembling IDP of the breast. Immunostaining with a set of immunohistochemical markers including AE/AE3, alpha-smooth muscle actin and p63 in combination with estrogen and progesterone receptors confirmed the diagnosis of ectopic IDP. This case shows that even though benign proliferative change in ectopic breast tissue is an extremely rare phe- nomenon, this possibility should be taken into account for correct diagnosis. Background right lobe of the gland, without familial history of breast Metastasis of breast cancer is most frequently