neonaucline, a new indole alkaloid from the leaves of ochreinauclea maingayii (hook. f.) ridsd. (rubiaceae)neonaucline,一个新的吲哚生物碱的叶子ochreinauclea maingayii(钩。.pdfVIP

Molecules 2012, 17, 267-274; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Neonaucline, a New Indole Alkaloid from the Leaves of Ochreinauclea maingayii (Hook. f.) Ridsd. (Rubiaceae) 1, 1 1 1 1 Mat Ropi Mukhtar *, Norfaizah Osman , Khalijah Awang , Hazrina Hazni , Ahmad Kaleem Qureshi , 1 2 2 3 A. Hamid A. Hadi , Kazuma Zaima , Hiroshi Morita and Marc Litaudon 1 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; E-Mails: faizah05@ (N.O.); khalijah@.my (K.A.); hazrinahazni@.my (H.H.); ahamid@.my (A.H.A.H.) 2 Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan; E-Mail: moritah@hoshi.ac.jp (H.M.) 3 Institut de Chimie de la Substances Naturelles, Centre Nationale de la Recherches Scientifique, 91198, Gif-sur Yvette, Cedex, France; E-Mail: marc.litaudon@rs-gif.fr (M.L.) * Author to whom correspondence should be addressed; E-Mail: matropi@.my; Tel.: +603-7967-4048; Fax: +603-7967-4193. Received: 25 October 2011; in revised form: 19 December 2011 / Accepted: 26 December 2011 / Published: 28 December 2011 Abstract: A new indole alkaloid; neonaucline (1), along with six known compounds– Cadamine (2), naucledine (3), harmane, benzamide, cinnamide and blumenol A–were isolated