outcome of postoperative critically ill patients with heparin-induced thrombocytopenia an observational retrospective case-control study结果术后危重患者的肝素诱发的血小板减少症观察回顾性病例对照研究.pdfVIP

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outcome of postoperative critically ill patients with heparin-induced thrombocytopenia an observational retrospective case-control study结果术后危重患者的肝素诱发的血小板减少症观察回顾性病例对照研究.pdf

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outcome of postoperative critically ill patients with heparin-induced thrombocytopenia an observational retrospective case-control study结果术后危重患者的肝素诱发的血小板减少症观察回顾性病例对照研究

Available online /content/10/6/R161 Vol 10 No 6 Open Access Research Outcome of postoperative critically ill patients with heparin-induced thrombocytopenia: an observational retrospective case-control study 1 2 3 1 Elise M Gettings , Kathryn A Brush , Elizabeth M Van Cott and William E Hurford 1Department of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA 2Department of Nursing, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA 3Department of Clinical Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA Corresponding author: William E Hurford, William.hurford@ Received: 31 Aug 2006 Revisions requested: 10 Oct 2006 Revisions received: 7 Nov 2006 Accepted: 16 Nov 2006 Published: 16 Nov 2006 Critical Care 2006, 10:R161 (doi:10.1186/cc5100) This article is online at: /content/10/6/R161 © 2006 Gettings et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Heparin-induced thrombocytopenia (HIT) is Nineteen patients (0.9% of admissions; 9% of tested described as a decrease in platelet count associated with individuals) had positive tests. HIT-antibody-positive patients, heparin administration and is an immune-mediated adverse drug compared with 19 matched controls, h