pea albumin 1 subunit b (pa1b), a promising bioinsecticide of plant origin豌豆蛋白1亚基b(pa1b),一个有前途的bioinsecticide植物起源.pdfVIP

Toxins 2011, 3, 1502-1517; doi:10.3390/toxins3121502 OPEN ACCESS toxins ISSN 2072-6651 /journal/toxins Review Pea Albumin 1 Subunit b (PA1b), a Promising Bioinsecticide of Plant Origin Frédéric Gressent *, Pedro Da Silva, Vanessa Eyraud, Lamis Karaki and Corinne Royer INSA-Lyon, INRA, Université de Lyon, UMR203 BF2I, Biologie Fonctionnelle Insectes et Interactions, Bat. Louis-Pasteur 20 av. Albert Einstein, Villeurbanne F-69621, France; E-Mails: Pedro.da-silva@insa-lyon.fr (P.D.S.); Vanessa.Eyraud@lyon.inra.fr (V.E.); Lamis.Karaki@lyon.inra.fr (L.K.); Corinne.Royer@lyon.inra.fr (C.R.) * Author to whom correspondence should be addressed; E-Mail: Frederic.Gressent@lyon.inra.fr; Tel.: +33-4-72-43-79-82; Fax: +33-4-72-43-82-34. Received: 23 September 2011; in revised form: 24 November 2011 / Accepted: 30 November 2011 / Published: 8 December 2011 Abstract: PA1b (Pea Albumin 1, subunit b) is a peptide extract from pea seeds showing significant insecticidal activity against certain insects, such as cereal weevils (genus Sitophilus), the mosquitoes Culex pipiens and Aedes aegyptii, and certain species of aphids. PA1b has great potential for use on an industrial scale and for use in organic farming: it is extracted from a common plant; it is a peptide (and therefore suitable for transgenic applications); it can withstand many steps of extraction and purification without losing its activity; and it is present in a seed regularly consumed by humans and mammals without any known toxicit